Diabetes Care: 44 (2)

February 01 2021; volume 44 issue 2

Perspectives in Care

Open Access
The Evolution of Hemoglobin A_1c Targets for Youth With Type 1 Diabetes: Rationale and Supporting Evidence
Maria J. Redondo, Ingrid Libman, David M. Maahs, Sarah K. Lyons, Mindy Saraco, Jane Reusch, Henry Rodriguez and Linda A. DiMeglio

Diabetes Care 2021 Feb; 44 (2): 301-312. https://doi.org/10.2337/dc20-1978

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Commentaries

Open Access
Apps and the Woman With Gestational Diabetes Mellitus
Jincy Immanuel and David Simmons

Diabetes Care 2021 Feb; 44 (2): 313-315. https://doi.org/10.2337/dci20-0068

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Open Access
Spontaneous or Deliberate: Effects of Acute Variations in Glycemia on Gastric Emptying in Type 1 Diabetes
Michael Horowitz, Tongzhi Wu, Christopher K. Rayner, Chinmay S. Marathe and Karen L. Jones

Diabetes Care 2021 Feb; 44 (2): 316-318. https://doi.org/10.2337/dci20-0067

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Open Access
The Prognostic Value of Time in Range in Type 2 Diabetes
Elizabeth Selvin

Diabetes Care 2021 Feb; 44 (2): 319-320. https://doi.org/10.2337/dci20-0066

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Clinical Care/Education/Nutrition/Psychosocial Research

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Presence of Liver Steatosis Is Associated With Greater Diabetes Remission After Gastric Bypass Surgery
Roman Vangoitsenhoven, Rickesha L. Wilson, Deepa V. Cherla, Chao Tu, Sangeeta R. Kashyap, David E. Cummings, Philip R. Schauer and Ali Aminian

Diabetes Care 2021 Feb; 44 (2): 321-325. https://doi.org/10.2337/dc20-0150

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Independent Observational Analysis of Ulcer Outcomes for SINBAD and University of Texas Ulcer Scoring Systems
Graham P. Leese, Enrique Soto-Pedre and Christopher Schofield

Diabetes Care 2021 Feb; 44 (2): 326-331. https://doi.org/10.2337/dc20-1817

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Open Access
Parent and Pediatrician Preferences for Type 1 Diabetes Screening in the U.S.
Jessica L. Dunne, Anne Koralova, Jessie Sutphin, Jesse S. Bushman, Barbara Fontanals-Ciera, Joshua R. Coulter, Campbell T. Hutton, Marian J. Rewers and Carol Mansfield

Diabetes Care 2021 Feb; 44 (2): 332-339. https://doi.org/10.2337/dc20-0927

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Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort
Neda Rasouli, Naji Younes, Kristina M. Utzschneider, Silvio E. Inzucchi, Ashok Balasubramanyam, Andrea L. Cherrington, Faramarz Ismail-Beigi, Robert M. Cohen, Darin E. Olson, Ralph A. DeFronzo, William H. Herman, John M. Lachin, Steven E. Kahn and the GRADE Research Group

Diabetes Care 2021 Feb; 44 (2): 340-349. https://doi.org/10.2337/dc20-1787

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Epidemiology/Health Services Research

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Association of Serum 25-Hydroxyvitamin D Concentrations With All-Cause and Cause-Specific Mortality Among Individuals With Diabetes
Zhenzhen Wan, Jingyu Guo, An Pan, Chen Chen, Liegang Liu and Gang Liu

Diabetes Care 2021 Feb; 44 (2): 350-357. https://doi.org/10.2337/dc20-1485

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Open Access
Interpretable Machine Learning Framework Reveals Robust Gut Microbiome Features Associated With Type 2 Diabetes
Wanglong Gou, Chu-wen Ling, Yan He, Zengliang Jiang, Yuanqing Fu, Fengzhe Xu, Zelei Miao, Ting-yu Sun, Jie-sheng Lin, Hui-lian Zhu, Hongwei Zhou, Yu-ming Chen and Ju-Sheng Zheng

Diabetes Care 2021 Feb; 44 (2): 358-366. https://doi.org/10.2337/dc20-1536

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Glycemic Control and Risk of Cellulitis
Galia Zacay, Fabienne Hershkowitz Sikron and Anthony D. Heymann

Diabetes Care 2021 Feb; 44 (2): 367-372. https://doi.org/10.2337/dc19-1393

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Open Access
Incremental Risk of Developing Severe COVID-19 Among Mexican Patients With Diabetes Attributed to Social and Health Care Access Disadvantages
Sandra G. Sosa-Rubí, Jacqueline A. Seiglie, Carlos Chivardi, Jennifer Manne-Goehler, James B. Meigs, Deborah J. Wexler, Veronika J. Wirtz, Octavio Gómez-Dantés and Edson Serván-Mori

Diabetes Care 2021 Feb; 44 (2): 373-380. https://doi.org/10.2337/dc20-2192

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Patient Health Utility Equations for a Type 2 Diabetes Model
Simon J. Neuwahl, Ping Zhang, Haiying Chen, Hui Shao, Michael Laxy, Andrea M. Anderson, Timothy E. Craven, Thomas J. Hoerger and the Look AHEAD Research Group

Diabetes Care 2021 Feb; 44 (2): 381-389. https://doi.org/10.2337/dc20-1207

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Clinical Impact of Residual C-Peptide Secretion in Type 1 Diabetes on Glycemia and Microvascular Complications
Anita Jeyam, Helen Colhoun, Stuart McGurnaghan, Luke Blackbourn, Timothy J. McDonald, Colin N.A. Palmer, John A. McKnight, Mark W.J. Strachan, Alan W. Patrick, John Chalmers, Robert S. Lindsay, John R. Petrie, Sandeep Thekkepat, Andrew Collier, Sandra MacRury and Paul M. McKeigue, on behalf of SDRNT1BIO Investigators

Diabetes Care 2021 Feb; 44 (2): 390-398. https://doi.org/10.2337/dc20-0567

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Open Access
Advanced Liver Fibrosis Is Common in Patients With Type 2 Diabetes Followed in the Outpatient Setting: The Need for Systematic Screening
Romina Lomonaco, Eddison Godinez Leiva, Fernando Bril, Sulav Shrestha, Lydia Mansour, Jeff Budd, Jessica Portillo Romero, Siegfried Schmidt, Ku-Lang Chang, George Samraj, John Malaty, Katherine Huber, Pierre Bedossa, Srilaxmi Kalavalapalli, Jonathan Marte, Diana Barb, Danielle Poulton, Nada Fanous and Kenneth Cusi

Diabetes Care 2021 Feb; 44 (2): 399-406. https://doi.org/10.2337/dc20-1997

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Health Care Use and Costs in Individuals With Diabetes With and Without Comorbid Depression in Germany: Results of the Cross-sectional DiaDec Study
Manuela Brüne, Ute Linnenkamp, Silke Andrich, Linda Jaffan-Kolb, Heiner Claessen, Charalabos-Markos Dintsios, Imke Schmitz-Losem, Johannes Kruse, Nadja Chernyak, Mickaël Hiligsmann, Norbert Hermanns and Andrea Icks

Diabetes Care 2021 Feb; 44 (2): 407-415. https://doi.org/10.2337/dc19-2487

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Open Access
Interaction Between GAD65 Antibodies and Dietary Fish Intake or Plasma Phospholipid n-3 Polyunsaturated Fatty Acids on Incident Adult-Onset Diabetes: The EPIC-InterAct Study
Josefin E. Löfvenborg, Sofia Carlsson, Tomas Andersson, Christiane S. Hampe, Albert Koulman, María Dolores Chirlaque Lopez, Paula Jakszyn, Verena A. Katzke, Tilman Kühn, Cecilie Kyrø, Giovanna Masala, Peter M. Nilsson, Kim Overvad, Salvatore Panico, Maria-Jose Sánchez, Yvonne van der Schouw, Matthias B. Schulze, Anne Tjønneland, Elisabete Weiderpass, Elio Riboli, Nita G. Forouhi, Stephen J. Sharp, Olov Rolandsson and Nicholas J. Wareham

Diabetes Care 2021 Feb; 44 (2): 416-424. https://doi.org/10.2337/dc20-1463

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Exercise During the First Trimester of Pregnancy and the Risks of Abnormal Screening and Gestational Diabetes Mellitus
Samantha F. Ehrlich, Assiamira Ferrara, Monique M. Hedderson, Juanran Feng and Romain Neugebauer

Diabetes Care 2021 Feb; 44 (2): 425-432. https://doi.org/10.2337/dc20-1475

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Emerging Therapies: Drugs and Regimens

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Durability of Triple Combination Therapy Versus Stepwise Addition Therapy in Patients With New-Onset T2DM: 3-Year Follow-up of EDICT
Muhammad Abdul-Ghani, Curtiss Puckett, John Adams, Ahmad Khattab, Gozde Baskoy, Eugenio Cersosimo, Curtis Triplitt and Ralph A. DeFronzo

Diabetes Care 2021 Feb; 44 (2): 433-439. https://doi.org/10.2337/dc20-0978

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Open Access
Natriuretic Effect of Two Weeks of Dapagliflozin Treatment in Patients With Type 2 Diabetes and Preserved Kidney Function During Standardized Sodium Intake: Results of the DAPASALT Trial
Rosalie A. Scholtes, Marcel H.A. Muskiet, Michiel J.B. van Baar, Anne C. Hesp, Peter J. Greasley, Cecilia Karlsson, Ann Hammarstedt, Niki Arya, Daniël H. van Raalte and Hiddo J.L. Heerspink

Diabetes Care 2021 Feb; 44 (2): 440-447. https://doi.org/10.2337/dc20-2604

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Open Access
Pharmacokinetics and Pharmacodynamics of Three Different Formulations of Insulin Aspart: A Randomized, Double-Blind, Crossover Study in Men With Type 1 Diabetes
Eva Svehlikova, Ines Mursic, Thomas Augustin, Christoph Magnes, David Gerring, Jan Jezek, Daniela Schwarzenbacher, Maria Ratzer, Michael Wolf, Sarah Howell, Leon Zakrzewski, Martina Urschitz, Bernd Tschapeller, Christina Gatschelhofer, Franz Feichtner, Fiona Lawrence and Thomas R. Pieber

Diabetes Care 2021 Feb; 44 (2): 448-455. https://doi.org/10.2337/dc20-1017

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Emerging Technologies: Data Systems and Devices

Open Access
A Randomized Controlled Trial to Evaluate the Effects of a Smartphone Application–Based Lifestyle Coaching Program on Gestational Weight Gain, Glycemic Control, and Maternal and Neonatal Outcomes in Women With Gestational Diabetes Mellitus: The SMART-GDM Study
Tong Wei Yew, Claudia Chi, Shiao-Yng Chan, Rob M. van Dam, Clare Whitton, Chang Siang Lim, Pin Sym Foong, Winni Fransisca, Chieu Leng Teoh, Jeannie Chen, Su Tin Ho-Lim, Su Lin Lim, Kai Wen Ong, Peck-Hoon Ong, Bee Choo Tai and E Shyong Tai

Diabetes Care 2021 Feb; 44 (2): 456-463. https://doi.org/10.2337/dc20-1216

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A Randomized Clinical Trial Assessing Continuous Glucose Monitoring (CGM) Use With Standardized Education With or Without a Family Behavioral Intervention Compared With Fingerstick Blood Glucose Monitoring in Very Young Children With Type 1 Diabetes
Strategies to Enhance New CGM Use in Early Childhood (SENCE) Study Group

Diabetes Care 2021 Feb; 44 (2): 464-472. https://doi.org/10.2337/dc20-1060

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Extended Use of the Control-IQ Closed-Loop Control System in Children With Type 1 Diabetes
Lauren G. Kanapka, R. Paul Wadwa, Marc D. Breton, Katrina J. Ruedy, Laya Ekhlaspour, Gregory P. Forlenza, Eda Cengiz, Melissa J. Schoelwer, Emily Jost, Lori Carria, Emma Emory, Liana J. Hsu, Stuart A. Weinzimer, Mark D. DeBoer, Bruce A. Buckingham, Mary Oliveri, Craig Kollman, Betsy B. Dokken, Daniel Cherñavvsky and Roy W. Beck, for the iDCL Trial Research Group

Diabetes Care 2021 Feb; 44 (2): 473-478. https://doi.org/10.2337/dc20-1729

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Pathophysiology/Complications

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Day-to-Day Variations in Fasting Plasma Glucose Do Not Influence Gastric Emptying in Subjects With Type 1 Diabetes
Lea Aigner, Björn Becker, Sonja Gerken, Daniel R. Quast, Juris J. Meier and Michael A. Nauck

Diabetes Care 2021 Feb; 44 (2): 479-488. https://doi.org/10.2337/dc20-1660

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Hepatic Insulin Resistance Is Not Pathway Selective in Humans With Nonalcoholic Fatty Liver Disease
Kasper W. ter Horst, Daniel F. Vatner, Dongyan Zhang, Gary W. Cline, Mariette T. Ackermans, Aart J. Nederveen, Joanne Verheij, Ahmet Demirkiran, Bart A. van Wagensveld, Geesje M. Dallinga-Thie, Max Nieuwdorp, Johannes A. Romijn, Gerald I. Shulman and Mireille J. Serlie

Diabetes Care 2021 Feb; 44 (2): 489-498. https://doi.org/10.2337/dc20-1644

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Association of Serum Bile Acids Profile and Pathway Dysregulation With the Risk of Developing Diabetes Among Normoglycemic Chinese Adults: Findings From the 4C Study
Jieli Lu, Shuangyuan Wang, Mian Li, Zhengnan Gao, Yu Xu, Xinjie Zhao, Chunyan Hu, Yi Zhang, Ruixin Liu, Ruying Hu, Lixin Shi, Ruizhi Zheng, Rui Du, Qing Su, Jiqiu Wang, Yuhong Chen, Xuefeng Yu, Li Yan, Tiange Wang, Zhiyun Zhao, Xiaolin Wang, Qi Li, Guijun Qin, Qin Wan, Gang Chen, Min Xu, Meng Dai, Di Zhang, Xulei Tang, Guixia Wang, Feixia Shen, Zuojie Luo, Yingfen Qin, Li Chen, Yanan Huo, Qiang Li, Zhen Ye, Yinfei Zhang, Chao Liu, Youmin Wang, Shengli Wu, Tao Yang, Huacong Deng, Donghui Li, Shenghan Lai, Yiming Mu, Lulu Chen, Jiajun Zhao, Guowang Xu, Guang Ning, Yufang Bi and Weiqing Wang, for the 4C Study Group

Diabetes Care 2021 Feb; 44 (2): 499-510. https://doi.org/10.2337/dc20-0884

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Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study
Roberto Bizzotto, Christopher Jennison, Angus G. Jones, Azra Kurbasic, Andrea Tura, Gwen Kennedy, Jimmy D. Bell, E. Louise Thomas, Gary Frost, Rebeca Eriksen, Robert W. Koivula, Soren Brage, Jane Kaye, Andrew T. Hattersley, Alison Heggie, Donna McEvoy, Leen M. ’t Hart, Joline W. Beulens, Petra Elders, Petra B. Musholt, Martin Ridderstråle, Tue H. Hansen, Kristine H. Allin, Torben Hansen, Henrik Vestergaard, Agnete T. Lundgaard, Henrik S. Thomsen, Federico De Masi, Konstantinos D. Tsirigos, Søren Brunak, Ana Viñuela, Anubha Mahajan, Timothy J. McDonald, Tarja Kokkola, Ian M. Forgie, Giuseppe N. Giordano, Imre Pavo, Hartmut Ruetten, Emmanouil Dermitzakis, Mark I. McCarthy, Oluf Pedersen, Jochen M. Schwenk, Jerzy Adamski, Paul W. Franks, Mark Walker, Ewan R. Pearson and Andrea Mari, for the IMI DIRECT consortium

Diabetes Care 2021 Feb; 44 (2): 511-518. https://doi.org/10.2337/dc20-1567

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High Prevalence of Advanced Liver Fibrosis Assessed by Transient Elastography Among U.S. Adults With Type 2 Diabetes
Stefano Ciardullo, Tommaso Monti and Gianluca Perseghin

Diabetes Care 2021 Feb; 44 (2): 519-525. https://doi.org/10.2337/dc20-1778

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Open Access
COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic’s Impact in Type 1 and Type 2 Diabetes
Justin M. Gregory, James C. Slaughter, Sara H. Duffus, T. Jordan Smith, Lauren M. LeStourgeon, Sarah S. Jaser, Allison B. McCoy, James M. Luther, Erin R. Giovannetti, Schafer Boeder, Jeremy H. Pettus and Daniel J. Moore

Diabetes Care 2021 Feb; 44 (2): 526-532. https://doi.org/10.2337/dc20-2260

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Restoration of Hypoglycemia Awareness Alters Brain Activity in Type 1 Diabetes
Munachiso Nwokolo, Stephanie A. Amiel, Owen O’Daly, Ian A. Macdonald, Fernando O. Zelaya and Pratik Choudhary

Diabetes Care 2021 Feb; 44 (2): 533-540. https://doi.org/10.2337/dc20-1250

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Gluconeogenesis, But Not Glycogenolysis, Contributes to the Increase in Endogenous Glucose Production by SGLT-2 Inhibition
Peter Wolf, Paul Fellinger, Lorenz Pfleger, Hannes Beiglböck, Patrik Krumpolec, Chiara Barbieri, Amalia Gastaldelli, Jürgen Harreiter, Matthäus Metz, Thomas Scherer, Maximilian Zeyda, Sabina Baumgartner-Parzer, Rodrig Marculescu, Siegfried Trattnig, Alexandra Kautzky-Willer, Martin Krššák and Michael Krebs

Diabetes Care 2021 Feb; 44 (2): 541-548. https://doi.org/10.2337/dc20-1983

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Cardiovascular and Metabolic Risk

Open Access
Time in Range in Relation to All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes: A Prospective Cohort Study
Jingyi Lu, Chunfang Wang, Yun Shen, Lei Chen, Lei Zhang, Jinghao Cai, Wei Lu, Wei Zhu, Gang Hu, Tian Xia and Jian Zhou

Diabetes Care 2021 Feb; 44 (2): 549-555. https://doi.org/10.2337/dc20-1862

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Open Access
Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis
Tricia M. Peters, Michael V. Holmes, J. Brent Richards, Tom Palmer, Vincenzo Forgetta, Cecilia M. Lindgren, Folkert W. Asselbergs, Christopher P. Nelson, Nilesh J. Samani, Mark I. McCarthy, Anubha Mahajan, George Davey Smith, Mark Woodward, Linda M. O’Keeffe and Sanne A.E. Peters

Diabetes Care 2021 Feb; 44 (2): 556-562. https://doi.org/10.2337/dc20-1137

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Sedentary Behavior and Diabetes Risk Among Women Over the Age of 65 Years: The OPACH Study
John Bellettiere, Michael J. LaMonte, Genevieve N. Healy, Sandy Liles, Kelly R. Evenson, Chongzhi Di, Jacqueline Kerr, I-Min Lee, Eileen Rillamas-Sun, David Buchner, Melbourne F. Hovell and Andrea Z. LaCroix

Diabetes Care 2021 Feb; 44 (2): 563-570. https://doi.org/10.2337/dc20-0709

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Association of Plasma Leucine-Rich α-2 Glycoprotein 1, a Modulator of Transforming Growth Factor-β Signaling Pathway, With Incident Heart Failure in Individuals With Type 2 Diabetes
Jian-Jun Liu, Sharon L.T. Pek, Jiexun Wang, Sylvia Liu, Keven Ang, Yi Ming Shao, Justin I.-Shing Tang, Resham L. Gurung, Subramaniam Tavintharan, Wern Ee Tang, Chee Fang Sum and Su Chi Lim

Diabetes Care 2021 Feb; 44 (2): 571-577. https://doi.org/10.2337/dc20-2065

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Open Access
Association Between Achieving Inpatient Glycemic Control and Clinical Outcomes in Hospitalized Patients With COVID-19: A Multicenter, Retrospective Hospital-Based Analysis
David C. Klonoff, Jordan C. Messler, Guillermo E. Umpierrez, Limin Peng, Robby Booth, Jennifer Crowe, Valerie Garrett, Raymie McFarland and Francisco J. Pasquel

Diabetes Care 2021 Feb; 44 (2): 578-585. https://doi.org/10.2337/dc20-1857

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Open Access
Dapagliflozin and the Incidence of Type 2 Diabetes in Patients With Heart Failure and Reduced Ejection Fraction: An Exploratory Analysis From DAPA-HF
Silvio E. Inzucchi, Kieran F. Docherty, Lars Køber, Mikhail N. Kosiborod, Felipe A. Martinez, Piotr Ponikowski, Marc S. Sabatine, Scott D. Solomon, Subodh Verma, Jan Bělohlávek, Michael Böhm, Chern-En Chiang, Rudolf A. de Boer, Mirta Diez, Andre Dukát, Charlotta E.A. Ljungman, Olof Bengtsson, Anna Maria Langkilde, Mikaela Sjöstrand, Pardeep S. Jhund and John J.V. McMurray, on behalf of the DAPA-HF Investigators and Committees

Diabetes Care 2021 Feb; 44 (2): 586-594. https://doi.org/10.2337/dc20-1675

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Comparison of Natriuretic Peptides as Risk Markers for All-Cause Mortality and Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes
Nete Tofte, Simone Theilade, Signe A. Winther, Sørine Birkelund, Jens P. Goetze, Tine W. Hansen and Peter Rossing

Diabetes Care 2021 Feb; 44 (2): 595-603. https://doi.org/10.2337/dc20-2107

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Novel Communications in Diabetes

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A Meal Detection Algorithm for the Artificial Pancreas: A Randomized Controlled Clinical Trial in Adolescents With Type 1 Diabetes
Emilie Palisaitis, Anas El Fathi, Julia E. von Oettingen, Ahmad Haidar and Laurent Legault

Diabetes Care 2021 Feb; 44 (2): 604-606. https://doi.org/10.2337/dc20-1232

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Good Glycemic Outcomes Following Bariatric Surgery Among Patients With Type 2 Diabetes, Obesity, and Low-Titer GAD Antibodies
Ruveena Kaur, David Kim, Richard Cutfield, Michael Booth, Lindsay Plank and Rinki Murphy

Diabetes Care 2021 Feb; 44 (2): 607-609. https://doi.org/10.2337/dc20-0804

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Open Access
Carbohydrate Requirements for Prolonged, Fasted Exercise With and Without Basal Rate Reductions in Adults With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion
Sarah M. McGaugh, Dessi P. Zaharieva, Rubin Pooni, Ninoschka C. D’Souza, Todd Vienneau, Trang T. Ly and Michael C. Riddell

Diabetes Care 2021 Feb; 44 (2): 610-613. https://doi.org/10.2337/dc20-1554

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Roux-en-Y Gastric Bypass Increases Glycemic Variability and Time in Hypoglycemia in Patients With Obesity and Prediabetes or Type 2 Diabetes: A Prospective Cohort Study
Ibiyemi Ilesanmi, George Tharakan, Kleopatra Alexiadou, Preeshila Behary, Haya Alessimii, Candace Bovill-Taylor, Julia Kenkre, Sirazum Choudhury, Chedie Doyle, Sanjay Purkayastha, Alex Miras, Christos Tsironis, Harvinder Chahal, Stephen R. Bloom, Nick S. Oliver, Ahmed R. Ahmed, Bernard Khoo and Tricia M.-M. Tan

Diabetes Care 2021 Feb; 44 (2): 614-617. https://doi.org/10.2337/dc20-1609

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Meta-analysis

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Effects of Vitamin C Supplementation on Glycemic Control and Cardiovascular Risk Factors in People With Type 2 Diabetes: A GRADE-Assessed Systematic Review and Meta-analysis of Randomized Controlled Trials
Shaun A. Mason, Michelle A. Keske and Glenn D. Wadley

Diabetes Care 2021 Feb; 44 (2): 618-630. https://doi.org/10.2337/dc20-1893

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Erratum

Open Access
Erratum. Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria. Diabetes Care 2020;43:2760–2767
Katsuhito Ihara, Jan Skupien, Hiroki Kobayashi, Zaipul I. Md Dom, Jonathan M. Wilson, Kristina O’Neil, Hannah S. Badger, Lenden M. Bowsman, Eiichiro Satake, Matthew D. Breyer, Kevin L. Duffin and Andrzej S. Krolewski

Diabetes Care 2021 Feb; 44 (2): 631. https://doi.org/10.2337/dc21-er02

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Issues and Events

Open Access
Issues and Events
Diabetes Care 2021 Feb; 44 (2): 632. https://doi.org/10.2337/dc21-ie02

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e-Letters

Observations
- Open Access
  Diabetes and COVID-19–Related Mortality in Women and Men in the UK Biobank: Comparisons With Influenza/Pneumonia and Coronary Heart Disease
  Marit de Jong, Mark Woodward and Sanne A.E. Peters
  
  Diabetes Care 2021 Feb; 44 (2): e22-e24. https://doi.org/10.2337/dc20-2378
  
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- Open Access
  Increased Hyperglycemia and Hospital-Acquired Infections Following Withdrawal of the RAPIDS Early Intervention Model of Diabetes Care in Medical and Surgical Inpatients
  Mervyn Kyi, Joanna Wang and Spiros Fourlanos
  
  Diabetes Care 2021 Feb; 44 (2): e25-e26. https://doi.org/10.2337/dc20-2469
  
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- Open Access
  Diabetic Foot Care Before and During the COVID-19 Epidemic: What Really Matters?
  Vilma Urbančič-Rovan
  
  Diabetes Care 2021 Feb; 44 (2): e27-e28. https://doi.org/10.2337/dc20-2650
  
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- Open Access
  Comparison of Diabetic Ketoacidosis in Adults During the SARS-CoV-2 Outbreak and Over the Same Time Period for the Preceding 3 Years
  Shivani Misra, Baktash Khozoee, Jiawei Huang, Kyriaki Mitsaki, Monika Reddy, Victoria Salem, Tricia Tan, George Tharakan, David Gable, Vassiliki Bravis and Jonathan Valabhji
  
  Diabetes Care 2021 Feb; 44 (2): e29-e31. https://doi.org/10.2337/dc20-2062
  
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- Open Access
  Use of Metformin and Cardiovascular Effects of New Classes of Glucose-Lowering Agents: A Meta-analysis of Cardiovascular Outcome Trials in Type 2 Diabetes
  Francesco Zaccardi, David E. Kloecker, John B. Buse, Chantal Mathieu, Kamlesh Khunti and Melanie J. Davies
  
  Diabetes Care 2021 Feb; 44 (2): e32-e34. https://doi.org/10.2337/dc20-2080
  
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Comment
- Open Access
  Comment on Piccinini and Bergman The Measurement of Insulin Clearance. Diabetes Care 2020;43:2296–2302
  Andrea Tura and Giovanni Pacini
  
  Diabetes Care 2021 Feb; 44 (2): e35. https://doi.org/10.2337/dc20-2444
  
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Table of Contents

Perspectives in Care

Commentaries

Clinical Care/Education/Nutrition/Psychosocial Research

Epidemiology/Health Services Research

Emerging Therapies: Drugs and Regimens

Emerging Technologies: Data Systems and Devices

Pathophysiology/Complications

Cardiovascular and Metabolic Risk

Novel Communications in Diabetes

Meta-analysis

Erratum

Issues and Events

e-Letters

Observations

Comment

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