Diabetes Care: 44 (3)

March 01 2021; volume 44 issue 3

Presidential Address

Open Access
50 Years of Behavioral Science in Diabetes: A 2020 Vision of the Future
Mary de Groot

Diabetes Care 2021 Mar; 44 (3): 633-640. https://doi.org/10.2337/dci20-0058

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Perspectives in Care

Open Access
Clinical Translation of Cardiovascular Outcome Trials in Type 2 Diabetes: Is There More or Is There Less Than Meets the Eye?
Ele Ferrannini and Julio Rosenstock

Diabetes Care 2021 Mar; 44 (3): 641-646. https://doi.org/10.2337/dc20-0913

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Open Access
Metformin Benefits: Another Example for Alternative Energy Substrate Mechanism?
Andrea Giaccari, Anna Solini, Simona Frontoni and Stefano Del Prato

Diabetes Care 2021 Mar; 44 (3): 647-654. https://doi.org/10.2337/dc20-1964

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Clinical Care/Education/Nutrition/Psychosocial Research

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Specific Dimensions of Depression Have Different Associations With Cognitive Decline in Older Adults With Type 2 Diabetes
Laili Soleimani, Ramit Ravona-Springer, Hung-Mo Lin, Xiaoyu Liu, Mary Sano, Anthony Heymann and Michal Schnaider Beeri

Diabetes Care 2021 Mar; 44 (3): 655-662. https://doi.org/10.2337/dc20-2031

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Changes in Plant-Based Diet Indices and Subsequent Risk of Type 2 Diabetes in Women and Men: Three U.S. Prospective Cohorts
Zhangling Chen, Jean-Philippe Drouin-Chartier, Yanping Li, Megu Y. Baden, JoAnn E. Manson, Walter C. Willett, Trudy Voortman, Frank B. Hu and Shilpa N. Bhupathiraju

Diabetes Care 2021 Mar; 44 (3): 663-671. https://doi.org/10.2337/dc20-1636

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Association of Oily and Nonoily Fish Consumption and Fish Oil Supplements With Incident Type 2 Diabetes: A Large Population-Based Prospective Study
Guo-Chong Chen, Rhonda Arthur, Li-Qiang Qin, Li-Hua Chen, Zhendong Mei, Yan Zheng, Yang Li, Tao Wang, Thomas E. Rohan and Qibin Qi

Diabetes Care 2021 Mar; 44 (3): 672-680. https://doi.org/10.2337/dc20-2328

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Novel Biochemical Markers of Glycemia to Predict Pregnancy Outcomes in Women With Type 1 Diabetes
Claire L. Meek, Diana Tundidor, Denice S. Feig, Jennifer M. Yamamoto, Eleanor M. Scott, Diane D. Ma, Jose A. Halperin, Helen R. Murphy and Rosa Corcoy, on behalf of the CONCEPTT Collaborative Group

Diabetes Care 2021 Mar; 44 (3): 681-689. https://doi.org/10.2337/dc20-2360

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Open Access
Not Only Diabetes but Also Prediabetes Leads to Functional Decline and Disability in Older Adults
Ying Shang, Laura Fratiglioni, Davide Liborio Vetrano, Abigail Dove, Anna-Karin Welmer and Weili Xu

Diabetes Care 2021 Mar; 44 (3): 690-698. https://doi.org/10.2337/dc20-2232

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Epidemiology/Health Services Research

Open Access
Thirty-Year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes
Michael Fang and Elizabeth Selvin

Diabetes Care 2021 Mar; 44 (3): 699-706. https://doi.org/10.2337/dc20-2304

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Open Access
Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women
Qi Jin, Ni Shi, Desmond Aroke, Dong Hoon Lee, Joshua J. Joseph, Macarius Donneyong, Darwin L. Conwell, Phil A. Hart, Xuehong Zhang, Steven K. Clinton, Zobeida Cruz-Monserrate, Theodore M. Brasky, Rebecca Jackson, Lesley F. Tinker, Simin Liu, Lawrence S. Phillips, Aladdin H. Shadyab, Rami Nassir, Wei Bao and Fred K. Tabung

Diabetes Care 2021 Mar; 44 (3): 707-714. https://doi.org/10.2337/dc20-2216

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Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
Kirthi Menon, Barbora de Courten, Danny Liew, Zanfina Ademi, Alice J. Owen, Dianna J. Magliano and Ella Zomer

Diabetes Care 2021 Mar; 44 (3): 715-721. https://doi.org/10.2337/dc20-1429

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Open Access
Temporal Trends in Incident Hospitalization for Diabetes-Related Foot Ulcer in Type 2 Diabetes: The Fremantle Diabetes Study
Emma J. Hamilton, Wendy A. Davis, Ranita Siru, Mendel Baba, Paul E. Norman and Timothy M.E. Davis

Diabetes Care 2021 Mar; 44 (3): 722-730. https://doi.org/10.2337/dc20-1743

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Open Access
Social Deprivation and Incident Diabetes-Related Foot Disease in Patients With Type 2 Diabetes: A Population-Based Cohort Study
Jenny Riley, Christina Antza, Punith Kempegowda, Anuradhaa Subramanian, Joht Singh Chandan, Krishna Gokhale, Neil Thomas, Christopher Sainsbury, Abd A. Tahrani and Krishnarajah Nirantharakumar

Diabetes Care 2021 Mar; 44 (3): 731-739. https://doi.org/10.2337/dc20-1027

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Trajectories of Childhood Adversity and Type 1 Diabetes: A Nationwide Study of One Million Children
Jessica Bengtsson, Andreas Rieckmann, Bendix Carstensen, Jannet Svensson, Marit E. Jørgensen and Naja H. Rod

Diabetes Care 2021 Mar; 44 (3): 740-747. https://doi.org/10.2337/dc20-1130

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Open Access
Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy
Charles C. Wykoff, Rahul N. Khurana, Quan Dong Nguyen, Scott P. Kelly, Flora Lum, Rebecca Hall, Ibrahim M. Abbass, Anna M. Abolian, Ivaylo Stoilov, Tu My To and Vincent Garmo

Diabetes Care 2021 Mar; 44 (3): 748-756. https://doi.org/10.2337/dc20-0413

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Open Access
Prediabetes, Diabetes, and the Risk of All-Cause and Cause-Specific Mortality in a Japanese Working Population: Japan Epidemiology Collaboration on Occupational Health Study
Zobida Islam, Shamima Akter, Yosuke Inoue, Huan Hu, Keisuke Kuwahara, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Hiroko Okazaki, Toshiaki Miyamoto, Takayuki Ogasawara, Naoko Sasaki, Akihiko Uehara, Makoto Yamamoto, Takeshi Kochi, Masafumi Eguchi, Taiki Shirasaka, Makiko Shimizu, Satsue Nagahama, Ai Hori, Teppei Imai, Akiko Nishihara, Kentaro Tomita, Tomofumi Sone, Maki Konishi, Isamu Kabe, Tetsuya Mizoue and Seitaro Dohi, for the Japan Epidemiology Collaboration on Occupational Health Study Group

Diabetes Care 2021 Mar; 44 (3): 757-764. https://doi.org/10.2337/dc20-1213

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Emerging Therapies: Drugs and Regimens

Open Access
Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
Juan P. Frias, Enzo Bonora, Luis Nevarez Ruiz, Ying G. Li, Zhuoxin Yu, Zvonko Milicevic, Raleigh Malik, M. Angelyn Bethel and David A. Cox

Diabetes Care 2021 Mar; 44 (3): 765-773. https://doi.org/10.2337/dc20-1473

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Open Access
Durable Effects of iGlarLixi Up to 52 Weeks in Type 2 Diabetes: The LixiLan-G Extension Study
Lawrence Blonde, Julio Rosenstock, Juan Frias, Andreas L. Birkenfeld, Elisabeth Niemoeller, Elisabeth Souhami, Chen Ji, Stefano Del Prato and Vanita R. Aroda

Diabetes Care 2021 Mar; 44 (3): 774-780. https://doi.org/10.2337/dc20-2023

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Emerging Technologies: Data Systems and Devices

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The SEE Study: Safety, Efficacy, and Equity of Implementing Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth
Risa M. Wolf, T.Y. Alvin Liu, Chrystal Thomas, Laura Prichett, Ingrid Zimmer‐Galler, Kerry Smith, Michael D. Abramoff and Roomasa Channa

Diabetes Care 2021 Mar; 44 (3): 781-787. https://doi.org/10.2337/dc20-1671

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Pathophysiology/Complications

Open Access
Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
Eleni Rebelos, Marco Bucci, Tomi Karjalainen, Vesa Oikonen, Alessandra Bertoldo, Jarna C. Hannukainen, Kirsi A. Virtanen, Aino Latva-Rasku, Jussi Hirvonen, Ilkka Heinonen, Riitta Parkkola, Markku Laakso, Ele Ferrannini, Patricia Iozzo, Lauri Nummenmaa and Pirjo Nuutila

Diabetes Care 2021 Mar; 44 (3): 788-794. https://doi.org/10.2337/dc20-1549

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Cardiovascular and Metabolic Risk

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Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes
Kalie L. Tommerdahl, Karl Baumgartner, Michal Schäfer, Petter Bjornstad, Isabella Melena, Shannon Hegemann, Amy D. Baumgartner, Laura Pyle, Melanie Cree-Green, Uyen Truong, Lorna Browne, Judith G. Regensteiner, Jane E.B. Reusch and Kristen J. Nadeau

Diabetes Care 2021 Mar; 44 (3): 795-803. https://doi.org/10.2337/dc20-1879

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Carbamylated HDL and Mortality Outcomes in Type 2 Diabetes
David T.W. Lui, Ching-Lung Cheung, Alan C.H. Lee, Ying Wong, Sammy W.M. Shiu and Kathryn C.B. Tan

Diabetes Care 2021 Mar; 44 (3): 804-809. https://doi.org/10.2337/dc20-2186

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Open Access
Serum Galectin-3 and Subsequent Risk of Coronary Heart Disease in Subjects With Childhood-Onset Type 1 Diabetes: A Cohort Study
Maryam Saeed, German Tapia, Inger Ariansen, Lars C. Stene, Ingebjørg Seljeflot, Grethe S. Tell, Torild Skrivarhaug and Geir Joner

Diabetes Care 2021 Mar; 44 (3): 810-816. https://doi.org/10.2337/dc20-1712

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OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function
Silva A. Arslanian, Laure El ghormli, Joon Young Kim, Ashley H. Tjaden, Elena Barengolts, Sonia Caprio, Tamara S. Hannon, Kieren J. Mather, Kristen J. Nadeau, Kristina M. Utzschneider and Steven E. Kahn, for the RISE Consortium

Diabetes Care 2021 Mar; 44 (3): 817-825. https://doi.org/10.2337/dc20-2134

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Comparative Effectiveness and Safety of Sodium–Glucose Cotransporter 2 Inhibitors Versus Glucagon-Like Peptide 1 Receptor Agonists in Older Adults
Elisabetta Patorno, Ajinkya Pawar, Lily G. Bessette, Dae H. Kim, Chintan Dave, Robert J. Glynn, Medha N. Munshi, Sebastian Schneeweiss, Deborah J. Wexler and Seoyoung C. Kim

Diabetes Care 2021 Mar; 44 (3): 826-835. https://doi.org/10.2337/dc20-1464

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Novel Communications in Diabetes

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Fully Closed Loop Glucose Control With a Bihormonal Artificial Pancreas in Adults With Type 1 Diabetes: An Outpatient, Randomized, Crossover Trial
Helga Blauw, A. Joannet Onvlee, Michel Klaassen, Arianne C. van Bon and J. Hans DeVries

Diabetes Care 2021 Mar; 44 (3): 836-838. https://doi.org/10.2337/dc20-2106

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Open Access
Stay-at-Home Orders During the COVID-19 Pandemic, an Opportunity to Improve Glucose Control Through Behavioral Changes in Type 1 Diabetes
Louis Potier, Boris Hansel, Etienne Larger, Jean-François Gautier, Daphné Carreira, Rachel Assemien, Olivier Lantieri, Jean-Pierre Riveline and Ronan Roussel

Diabetes Care 2021 Mar; 44 (3): 839-843. https://doi.org/10.2337/dc20-2019

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Diabeloop DBLG1 Closed-Loop System Enables Patients With Type 1 Diabetes to Significantly Improve Their Glycemic Control in Real-Life Situations Without Serious Adverse Events: 6-Month Follow-up
Coralie Amadou, Sylvia Franc, Pierre-Yves Benhamou, Sandrine Lablanche, Erik Huneker, Guillaume Charpentier and Alfred Penfornis, on behalf of the Diabeloop Consortium

Diabetes Care 2021 Mar; 44 (3): 844-846. https://doi.org/10.2337/dc20-1809

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Open Access
Continuous Glucose Monitoring in the Intensive Care Unit During the COVID-19 Pandemic
Shivani Agarwal, Justin Mathew, Georgia M. Davis, Alethea Shephardson, Ann Levine, Rita Louard, Agustina Urrutia, Citlalli Perez-Guzman, Guillermo E. Umpierrez, Limin Peng and Francisco J. Pasquel

Diabetes Care 2021 Mar; 44 (3): 847-849. https://doi.org/10.2337/dc20-2219

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Open Access
The Effect of BMI and Type 2 Diabetes on Socioeconomic Status: A Two-Sample Multivariable Mendelian Randomization Study
Sara Pedron, Christoph F. Kurz, Lars Schwettmann and Michael Laxy

Diabetes Care 2021 Mar; 44 (3): 850-852. https://doi.org/10.2337/dc20-1721

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Issues and Events

Open Access
Issues and Events
Diabetes Care 2021 Mar; 44 (3): 853. https://doi.org/10.2337/dc21-ie03

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e-Letters

Observations
- Open Access
  DPP-4 Inhibitors and Respiratory Infection: A Systematic Review and Meta-analysis of the Cardiovascular Outcomes Trials
  Guillaume Grenet, Samia Mekhaldi, Sabine Mainbourg, Marine Auffret, Catherine Cornu, Jean-Luc Cracowski, François Gueyffier, Jean-Christophe Lega and Michel Cucherat
  
  Diabetes Care 2021 Mar; 44 (3): e36-e37. https://doi.org/10.2337/dc20-2018
  
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- Open Access
  Citizenship Status and Prevalence of Diagnosed and Undiagnosed Hypertension and Diabetes Among Adults in the U.S., 2011–2016
  Kazumi Tsuchiya and Ryan T. Demmer
  
  Diabetes Care 2021 Mar; 44 (3): e38-e39. https://doi.org/10.2337/dc20-2453
  
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- Open Access
  Severe Hypoglycemia and Risk of Atherosclerotic Cardiovascular Disease in Patients With Diabetes
  Jamal S. Rana, Howard H. Moffet, Jennifer Y. Liu and Andrew J. Karter
  
  Diabetes Care 2021 Mar; 44 (3): e40-e41. https://doi.org/10.2337/dc20-2798
  
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- Open Access
  Effects of Lifestyle Intervention of Maternal Gestational Diabetes Mellitus on Offspring Growth Pattern Before Two Years of Age
  Jing Li, Jinnan Liu, Cuiping Zhang, Gongshu Liu, Junhong Leng, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Juliana C.N. Chan and Xilin Yang
  
  Diabetes Care 2021 Mar; 44 (3): e42-e44. https://doi.org/10.2337/dc20-2750
  
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- Open Access
  Changes in Cardiovascular Biomarkers Associated With the Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitor Ertugliflozin in Patients With Chronic Kidney Disease and Type 2 Diabetes
  Patrick R. Lawler, Hongyan Liu, Claudia Frankfurter, Leif Erik Lovblom, Yuliya Lytvyn, Dylan Burger, Kevin D. Burns, Davor Brinc and David Z.I. Cherney
  
  Diabetes Care 2021 Mar; 44 (3): e45-e47. https://doi.org/10.2337/dc20-2265
  
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- Open Access
  Comparison of Diagnostic Accuracy for Lower-Extremity Amputation Codes During the ICD-9 and ICD-10 Eras in a High-Risk Population of Patients With Diabetes
  Alyson J. Littman, Andrew K. Timmons, Kathryn P. Moore, Chin-Lin Tseng, Gregory Landry, Jeffrey M. Robbins, Anna Korpak and Edward J. Boyko
  
  Diabetes Care 2021 Mar; 44 (3): e48-e49. https://doi.org/10.2337/dc20-2452
  
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- Open Access
  Continuous Glucose Monitoring in the Operating Room and Cardiac Intensive Care Unit
  M. Citlalli Perez-Guzman, Elizabeth Duggan, Seid Gibanica, Saumeth Cardona, Andrea Corujo-Rodriguez, Abimbola Faloye, Michael Halkos, Guillermo E. Umpierrez, Limin Peng, Georgia M. Davis and Francisco J. Pasquel
  
  Diabetes Care 2021 Mar; 44 (3): e50-e52. https://doi.org/10.2337/dc20-2386
  
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- Open Access
  Vertebral Ischemic Necrosis in Diabetic Lumbosacral Radiculoplexus Neuropathy
  Ari Breiner, Thanh B. Nguyen, Bibianna Purgina and Pierre R. Bourque
  
  Diabetes Care 2021 Mar; 44 (3): e53-e54. https://doi.org/10.2337/dc20-2787
  
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- Open Access
  Early Worsening of Diabetic Nephropathy in Type 2 Diabetes After Rapid Improvement in Chronic Severe Hyperglycemia
  Tim Cundy, Andrew Holden and Elizabeth Stallworthy
  
  Diabetes Care 2021 Mar; 44 (3): e55-e56. https://doi.org/10.2337/dc20-2646
  
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- Open Access
  Degree of Cardiometabolic Risk Factor Normalization in Individuals Receiving Bariatric Surgery: Evidence From NHANES 2015–2018
  Young-Rock Hong, Aaron S. Kelly, Crystal Johnson-Mann, Dominick J. Lemas and Michelle I. Cardel
  
  Diabetes Care 2021 Mar; 44 (3): e57-e58. https://doi.org/10.2337/dc20-2748
  
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Comments and Responses
- Open Access
  Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
  Geremia B. Bolli, Francesca Porcellati, Paola Lucidi and Carmine G. Fanelli
  
  Diabetes Care 2021 Mar; 44 (3): e59-e60. https://doi.org/10.2337/dc20-2575
  
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- Open Access
  Response to Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
  Roselle A. Herring, Fariba Shojaee-Moradie, Robert Garesse, Mary Stevenage, Nicola Jackson, Barbara A. Fielding, Agampodi Mendis, Sigurd Johnsen, A. Margot Umpleby, Melanie Davies and David L. Russell-Jones
  
  Diabetes Care 2021 Mar; 44 (3): e61. https://doi.org/10.2337/dci20-0072
  
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Table of Contents

Presidential Address

Perspectives in Care

Clinical Care/Education/Nutrition/Psychosocial Research

Epidemiology/Health Services Research

Emerging Therapies: Drugs and Regimens

Emerging Technologies: Data Systems and Devices

Pathophysiology/Complications

Cardiovascular and Metabolic Risk

Novel Communications in Diabetes

Issues and Events

e-Letters

Observations

Comments and Responses

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