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Table of Contents

Previous

March 01 2021; volume 44 issue 3

Presidential Address

  • Open Access
    50 Years of Behavioral Science in Diabetes: A 2020 Vision of the Future
    Mary de Groot
    Diabetes Care 2021 Mar; 44 (3): 633-640. https://doi.org/10.2337/dci20-0058
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Perspectives in Care

  • Open Access
    Clinical Translation of Cardiovascular Outcome Trials in Type 2 Diabetes: Is There More or Is There Less Than Meets the Eye?
    Ele Ferrannini and Julio Rosenstock
    Diabetes Care 2021 Mar; 44 (3): 641-646. https://doi.org/10.2337/dc20-0913
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  • Open Access
    Metformin Benefits: Another Example for Alternative Energy Substrate Mechanism?
    Andrea Giaccari, Anna Solini, Simona Frontoni and Stefano Del Prato
    Diabetes Care 2021 Mar; 44 (3): 647-654. https://doi.org/10.2337/dc20-1964
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Clinical Care/Education/Nutrition/Psychosocial Research

  • You have accessRestricted Access
    Specific Dimensions of Depression Have Different Associations With Cognitive Decline in Older Adults With Type 2 Diabetes
    Laili Soleimani, Ramit Ravona-Springer, Hung-Mo Lin, Xiaoyu Liu, Mary Sano, Anthony Heymann and Michal Schnaider Beeri
    Diabetes Care 2021 Mar; 44 (3): 655-662. https://doi.org/10.2337/dc20-2031
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    Changes in Plant-Based Diet Indices and Subsequent Risk of Type 2 Diabetes in Women and Men: Three U.S. Prospective Cohorts
    Zhangling Chen, Jean-Philippe Drouin-Chartier, Yanping Li, Megu Y. Baden, JoAnn E. Manson, Walter C. Willett, Trudy Voortman, Frank B. Hu and Shilpa N. Bhupathiraju
    Diabetes Care 2021 Mar; 44 (3): 663-671. https://doi.org/10.2337/dc20-1636
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    Association of Oily and Nonoily Fish Consumption and Fish Oil Supplements With Incident Type 2 Diabetes: A Large Population-Based Prospective Study
    Guo-Chong Chen, Rhonda Arthur, Li-Qiang Qin, Li-Hua Chen, Zhendong Mei, Yan Zheng, Yang Li, Tao Wang, Thomas E. Rohan and Qibin Qi
    Diabetes Care 2021 Mar; 44 (3): 672-680. https://doi.org/10.2337/dc20-2328
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    Novel Biochemical Markers of Glycemia to Predict Pregnancy Outcomes in Women With Type 1 Diabetes
    Claire L. Meek, Diana Tundidor, Denice S. Feig, Jennifer M. Yamamoto, Eleanor M. Scott, Diane D. Ma, Jose A. Halperin, Helen R. Murphy and Rosa Corcoy, on behalf of the CONCEPTT Collaborative Group
    Diabetes Care 2021 Mar; 44 (3): 681-689. https://doi.org/10.2337/dc20-2360
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  • Open Access
    Not Only Diabetes but Also Prediabetes Leads to Functional Decline and Disability in Older Adults
    Ying Shang, Laura Fratiglioni, Davide Liborio Vetrano, Abigail Dove, Anna-Karin Welmer and Weili Xu
    Diabetes Care 2021 Mar; 44 (3): 690-698. https://doi.org/10.2337/dc20-2232
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Epidemiology/Health Services Research

  • Open Access
    Thirty-Year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes
    Michael Fang and Elizabeth Selvin
    Diabetes Care 2021 Mar; 44 (3): 699-706. https://doi.org/10.2337/dc20-2304
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  • Open Access
    Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Type 2 Diabetes Risk in Postmenopausal Women
    Qi Jin, Ni Shi, Desmond Aroke, Dong Hoon Lee, Joshua J. Joseph, Macarius Donneyong, Darwin L. Conwell, Phil A. Hart, Xuehong Zhang, Steven K. Clinton, Zobeida Cruz-Monserrate, Theodore M. Brasky, Rebecca Jackson, Lesley F. Tinker, Simin Liu, Lawrence S. Phillips, Aladdin H. Shadyab, Rami Nassir, Wei Bao and Fred K. Tabung
    Diabetes Care 2021 Mar; 44 (3): 707-714. https://doi.org/10.2337/dc20-2216
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  • You have accessRestricted Access
    Productivity Benefits of Preventing Type 2 Diabetes in Australia: A 10-Year Analysis
    Kirthi Menon, Barbora de Courten, Danny Liew, Zanfina Ademi, Alice J. Owen, Dianna J. Magliano and Ella Zomer
    Diabetes Care 2021 Mar; 44 (3): 715-721. https://doi.org/10.2337/dc20-1429
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  • Open Access
    Temporal Trends in Incident Hospitalization for Diabetes-Related Foot Ulcer in Type 2 Diabetes: The Fremantle Diabetes Study
    Emma J. Hamilton, Wendy A. Davis, Ranita Siru, Mendel Baba, Paul E. Norman and Timothy M.E. Davis
    Diabetes Care 2021 Mar; 44 (3): 722-730. https://doi.org/10.2337/dc20-1743
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  • Open Access
    Social Deprivation and Incident Diabetes-Related Foot Disease in Patients With Type 2 Diabetes: A Population-Based Cohort Study
    Jenny Riley, Christina Antza, Punith Kempegowda, Anuradhaa Subramanian, Joht Singh Chandan, Krishna Gokhale, Neil Thomas, Christopher Sainsbury, Abd A. Tahrani and Krishnarajah Nirantharakumar
    Diabetes Care 2021 Mar; 44 (3): 731-739. https://doi.org/10.2337/dc20-1027
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    Trajectories of Childhood Adversity and Type 1 Diabetes: A Nationwide Study of One Million Children
    Jessica Bengtsson, Andreas Rieckmann, Bendix Carstensen, Jannet Svensson, Marit E. Jørgensen and Naja H. Rod
    Diabetes Care 2021 Mar; 44 (3): 740-747. https://doi.org/10.2337/dc20-1130
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  • Open Access
    Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy
    Charles C. Wykoff, Rahul N. Khurana, Quan Dong Nguyen, Scott P. Kelly, Flora Lum, Rebecca Hall, Ibrahim M. Abbass, Anna M. Abolian, Ivaylo Stoilov, Tu My To and Vincent Garmo
    Diabetes Care 2021 Mar; 44 (3): 748-756. https://doi.org/10.2337/dc20-0413
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  • Open Access
    Prediabetes, Diabetes, and the Risk of All-Cause and Cause-Specific Mortality in a Japanese Working Population: Japan Epidemiology Collaboration on Occupational Health Study
    Zobida Islam, Shamima Akter, Yosuke Inoue, Huan Hu, Keisuke Kuwahara, Tohru Nakagawa, Toru Honda, Shuichiro Yamamoto, Hiroko Okazaki, Toshiaki Miyamoto, Takayuki Ogasawara, Naoko Sasaki, Akihiko Uehara, Makoto Yamamoto, Takeshi Kochi, Masafumi Eguchi, Taiki Shirasaka, Makiko Shimizu, Satsue Nagahama, Ai Hori, Teppei Imai, Akiko Nishihara, Kentaro Tomita, Tomofumi Sone, Maki Konishi, Isamu Kabe, Tetsuya Mizoue and Seitaro Dohi, for the Japan Epidemiology Collaboration on Occupational Health Study Group
    Diabetes Care 2021 Mar; 44 (3): 757-764. https://doi.org/10.2337/dc20-1213
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Emerging Therapies: Drugs and Regimens

  • Open Access
    Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)
    Juan P. Frias, Enzo Bonora, Luis Nevarez Ruiz, Ying G. Li, Zhuoxin Yu, Zvonko Milicevic, Raleigh Malik, M. Angelyn Bethel and David A. Cox
    Diabetes Care 2021 Mar; 44 (3): 765-773. https://doi.org/10.2337/dc20-1473
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  • Open Access
    Durable Effects of iGlarLixi Up to 52 Weeks in Type 2 Diabetes: The LixiLan-G Extension Study
    Lawrence Blonde, Julio Rosenstock, Juan Frias, Andreas L. Birkenfeld, Elisabeth Niemoeller, Elisabeth Souhami, Chen Ji, Stefano Del Prato and Vanita R. Aroda
    Diabetes Care 2021 Mar; 44 (3): 774-780. https://doi.org/10.2337/dc20-2023
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Emerging Technologies: Data Systems and Devices

  • You have accessRestricted Access
    The SEE Study: Safety, Efficacy, and Equity of Implementing Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth
    Risa M. Wolf, T.Y. Alvin Liu, Chrystal Thomas, Laura Prichett, Ingrid Zimmer‐Galler, Kerry Smith, Michael D. Abramoff and Roomasa Channa
    Diabetes Care 2021 Mar; 44 (3): 781-787. https://doi.org/10.2337/dc20-1671
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Pathophysiology/Complications

  • Open Access
    Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort
    Eleni Rebelos, Marco Bucci, Tomi Karjalainen, Vesa Oikonen, Alessandra Bertoldo, Jarna C. Hannukainen, Kirsi A. Virtanen, Aino Latva-Rasku, Jussi Hirvonen, Ilkka Heinonen, Riitta Parkkola, Markku Laakso, Ele Ferrannini, Patricia Iozzo, Lauri Nummenmaa and Pirjo Nuutila
    Diabetes Care 2021 Mar; 44 (3): 788-794. https://doi.org/10.2337/dc20-1549
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Cardiovascular and Metabolic Risk

  • You have accessRestricted Access
    Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes
    Kalie L. Tommerdahl, Karl Baumgartner, Michal Schäfer, Petter Bjornstad, Isabella Melena, Shannon Hegemann, Amy D. Baumgartner, Laura Pyle, Melanie Cree-Green, Uyen Truong, Lorna Browne, Judith G. Regensteiner, Jane E.B. Reusch and Kristen J. Nadeau
    Diabetes Care 2021 Mar; 44 (3): 795-803. https://doi.org/10.2337/dc20-1879
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  • You have accessRestricted Access
    Carbamylated HDL and Mortality Outcomes in Type 2 Diabetes
    David T.W. Lui, Ching-Lung Cheung, Alan C.H. Lee, Ying Wong, Sammy W.M. Shiu and Kathryn C.B. Tan
    Diabetes Care 2021 Mar; 44 (3): 804-809. https://doi.org/10.2337/dc20-2186
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  • Open Access
    Serum Galectin-3 and Subsequent Risk of Coronary Heart Disease in Subjects With Childhood-Onset Type 1 Diabetes: A Cohort Study
    Maryam Saeed, German Tapia, Inger Ariansen, Lars C. Stene, Ingebjørg Seljeflot, Grethe S. Tell, Torild Skrivarhaug and Geir Joner
    Diabetes Care 2021 Mar; 44 (3): 810-816. https://doi.org/10.2337/dc20-1712
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    OGTT Glucose Response Curves, Insulin Sensitivity, and β-Cell Function in RISE: Comparison Between Youth and Adults at Randomization and in Response to Interventions to Preserve β-Cell Function
    Silva A. Arslanian, Laure El ghormli, Joon Young Kim, Ashley H. Tjaden, Elena Barengolts, Sonia Caprio, Tamara S. Hannon, Kieren J. Mather, Kristen J. Nadeau, Kristina M. Utzschneider and Steven E. Kahn, for the RISE Consortium
    Diabetes Care 2021 Mar; 44 (3): 817-825. https://doi.org/10.2337/dc20-2134
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  • You have accessRestricted Access
    Comparative Effectiveness and Safety of Sodium–Glucose Cotransporter 2 Inhibitors Versus Glucagon-Like Peptide 1 Receptor Agonists in Older Adults
    Elisabetta Patorno, Ajinkya Pawar, Lily G. Bessette, Dae H. Kim, Chintan Dave, Robert J. Glynn, Medha N. Munshi, Sebastian Schneeweiss, Deborah J. Wexler and Seoyoung C. Kim
    Diabetes Care 2021 Mar; 44 (3): 826-835. https://doi.org/10.2337/dc20-1464
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Novel Communications in Diabetes

  • You have accessRestricted Access
    Fully Closed Loop Glucose Control With a Bihormonal Artificial Pancreas in Adults With Type 1 Diabetes: An Outpatient, Randomized, Crossover Trial
    Helga Blauw, A. Joannet Onvlee, Michel Klaassen, Arianne C. van Bon and J. Hans DeVries
    Diabetes Care 2021 Mar; 44 (3): 836-838. https://doi.org/10.2337/dc20-2106
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  • Open Access
    Stay-at-Home Orders During the COVID-19 Pandemic, an Opportunity to Improve Glucose Control Through Behavioral Changes in Type 1 Diabetes
    Louis Potier, Boris Hansel, Etienne Larger, Jean-François Gautier, Daphné Carreira, Rachel Assemien, Olivier Lantieri, Jean-Pierre Riveline and Ronan Roussel
    Diabetes Care 2021 Mar; 44 (3): 839-843. https://doi.org/10.2337/dc20-2019
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  • You have accessRestricted Access
    Diabeloop DBLG1 Closed-Loop System Enables Patients With Type 1 Diabetes to Significantly Improve Their Glycemic Control in Real-Life Situations Without Serious Adverse Events: 6-Month Follow-up
    Coralie Amadou, Sylvia Franc, Pierre-Yves Benhamou, Sandrine Lablanche, Erik Huneker, Guillaume Charpentier and Alfred Penfornis, on behalf of the Diabeloop Consortium
    Diabetes Care 2021 Mar; 44 (3): 844-846. https://doi.org/10.2337/dc20-1809
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  • Open Access
    Continuous Glucose Monitoring in the Intensive Care Unit During the COVID-19 Pandemic
    Shivani Agarwal, Justin Mathew, Georgia M. Davis, Alethea Shephardson, Ann Levine, Rita Louard, Agustina Urrutia, Citlalli Perez-Guzman, Guillermo E. Umpierrez, Limin Peng and Francisco J. Pasquel
    Diabetes Care 2021 Mar; 44 (3): 847-849. https://doi.org/10.2337/dc20-2219
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  • Open Access
    The Effect of BMI and Type 2 Diabetes on Socioeconomic Status: A Two-Sample Multivariable Mendelian Randomization Study
    Sara Pedron, Christoph F. Kurz, Lars Schwettmann and Michael Laxy
    Diabetes Care 2021 Mar; 44 (3): 850-852. https://doi.org/10.2337/dc20-1721
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Issues and Events

  • Open Access
    Issues and Events
    Diabetes Care 2021 Mar; 44 (3): 853. https://doi.org/10.2337/dc21-ie03
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e-Letters

  • Observations

    • Open Access
      DPP-4 Inhibitors and Respiratory Infection: A Systematic Review and Meta-analysis of the Cardiovascular Outcomes Trials
      Guillaume Grenet, Samia Mekhaldi, Sabine Mainbourg, Marine Auffret, Catherine Cornu, Jean-Luc Cracowski, François Gueyffier, Jean-Christophe Lega and Michel Cucherat
      Diabetes Care 2021 Mar; 44 (3): e36-e37. https://doi.org/10.2337/dc20-2018
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    • Open Access
      Citizenship Status and Prevalence of Diagnosed and Undiagnosed Hypertension and Diabetes Among Adults in the U.S., 2011–2016
      Kazumi Tsuchiya and Ryan T. Demmer
      Diabetes Care 2021 Mar; 44 (3): e38-e39. https://doi.org/10.2337/dc20-2453
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    • Open Access
      Severe Hypoglycemia and Risk of Atherosclerotic Cardiovascular Disease in Patients With Diabetes
      Jamal S. Rana, Howard H. Moffet, Jennifer Y. Liu and Andrew J. Karter
      Diabetes Care 2021 Mar; 44 (3): e40-e41. https://doi.org/10.2337/dc20-2798
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    • Open Access
      Effects of Lifestyle Intervention of Maternal Gestational Diabetes Mellitus on Offspring Growth Pattern Before Two Years of Age
      Jing Li, Jinnan Liu, Cuiping Zhang, Gongshu Liu, Junhong Leng, Leishen Wang, Weiqin Li, Zhijie Yu, Gang Hu, Juliana C.N. Chan and Xilin Yang
      Diabetes Care 2021 Mar; 44 (3): e42-e44. https://doi.org/10.2337/dc20-2750
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    • Open Access
      Changes in Cardiovascular Biomarkers Associated With the Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitor Ertugliflozin in Patients With Chronic Kidney Disease and Type 2 Diabetes
      Patrick R. Lawler, Hongyan Liu, Claudia Frankfurter, Leif Erik Lovblom, Yuliya Lytvyn, Dylan Burger, Kevin D. Burns, Davor Brinc and David Z.I. Cherney
      Diabetes Care 2021 Mar; 44 (3): e45-e47. https://doi.org/10.2337/dc20-2265
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    • Open Access
      Comparison of Diagnostic Accuracy for Lower-Extremity Amputation Codes During the ICD-9 and ICD-10 Eras in a High-Risk Population of Patients With Diabetes
      Alyson J. Littman, Andrew K. Timmons, Kathryn P. Moore, Chin-Lin Tseng, Gregory Landry, Jeffrey M. Robbins, Anna Korpak and Edward J. Boyko
      Diabetes Care 2021 Mar; 44 (3): e48-e49. https://doi.org/10.2337/dc20-2452
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    • Open Access
      Continuous Glucose Monitoring in the Operating Room and Cardiac Intensive Care Unit
      M. Citlalli Perez-Guzman, Elizabeth Duggan, Seid Gibanica, Saumeth Cardona, Andrea Corujo-Rodriguez, Abimbola Faloye, Michael Halkos, Guillermo E. Umpierrez, Limin Peng, Georgia M. Davis and Francisco J. Pasquel
      Diabetes Care 2021 Mar; 44 (3): e50-e52. https://doi.org/10.2337/dc20-2386
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    • Open Access
      Vertebral Ischemic Necrosis in Diabetic Lumbosacral Radiculoplexus Neuropathy
      Ari Breiner, Thanh B. Nguyen, Bibianna Purgina and Pierre R. Bourque
      Diabetes Care 2021 Mar; 44 (3): e53-e54. https://doi.org/10.2337/dc20-2787
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    • Open Access
      Early Worsening of Diabetic Nephropathy in Type 2 Diabetes After Rapid Improvement in Chronic Severe Hyperglycemia
      Tim Cundy, Andrew Holden and Elizabeth Stallworthy
      Diabetes Care 2021 Mar; 44 (3): e55-e56. https://doi.org/10.2337/dc20-2646
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    • Open Access
      Degree of Cardiometabolic Risk Factor Normalization in Individuals Receiving Bariatric Surgery: Evidence From NHANES 2015–2018
      Young-Rock Hong, Aaron S. Kelly, Crystal Johnson-Mann, Dominick J. Lemas and Michelle I. Cardel
      Diabetes Care 2021 Mar; 44 (3): e57-e58. https://doi.org/10.2337/dc20-2748
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  • Comments and Responses

    • Open Access
      Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
      Geremia B. Bolli, Francesca Porcellati, Paola Lucidi and Carmine G. Fanelli
      Diabetes Care 2021 Mar; 44 (3): e59-e60. https://doi.org/10.2337/dc20-2575
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    • Open Access
      Response to Comment on Herring et al. Metabolic Effects of an SGLT2 Inhibitor (Dapagliflozin) During a Period of Acute Insulin Withdrawal and Development of Ketoacidosis in People With Type 1 Diabetes. Diabetes Care 2020;43:2128–2136
      Roselle A. Herring, Fariba Shojaee-Moradie, Robert Garesse, Mary Stevenage, Nicola Jackson, Barbara A. Fielding, Agampodi Mendis, Sigurd Johnsen, A. Margot Umpleby, Melanie Davies and David L. Russell-Jones
      Diabetes Care 2021 Mar; 44 (3): e61. https://doi.org/10.2337/dci20-0072
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Diabetes Care: 44 (3)

In this Issue

March 2021, 44(3)
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  • Presidential Address
  • Perspectives in Care
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  • Epidemiology/Health Services Research
  • Emerging Therapies: Drugs and Regimens
  • Emerging Technologies: Data Systems and Devices
  • Pathophysiology/Complications
  • Cardiovascular and Metabolic Risk
  • Novel Communications in Diabetes
  • Issues and Events
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    • Observations
    • Comments and Responses
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  • 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2021
  • 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021
  • Table 1—Système International (SI) units for plasma, serum, or blood concentrations
  • 6. Glycemic Targets: Standards of Medical Care in Diabetes—2021
  • 10. Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2021
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© 2021 by the American Diabetes Association. Diabetes Care Print ISSN: 0149-5992, Online ISSN: 1935-5548.