Skip to main content
  • More from ADA
    • Diabetes
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care
  • Subscribe
  • Log in
  • My Cart
  • Follow ada on Twitter
  • RSS
  • Visit ada on Facebook
Diabetes Care

Advanced Search

Main menu

  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • Special Article Collections
    • ADA Standards of Medical Care
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • Special Article Collections
    • ADA Standards of Medical Care
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Journal Policies
    • Instructions for Authors
    • ADA Peer Review
  • More from ADA
    • Diabetes
    • Clinical Diabetes
    • Diabetes Spectrum
    • ADA Standards of Medical Care
    • ADA Scientific Sessions Abstracts
    • BMJ Open Diabetes Research & Care

User menu

  • Subscribe
  • Log in
  • My Cart

Search

  • Advanced search
Diabetes Care
  • Home
  • Current
    • Current Issue
    • Online Ahead of Print
    • Special Article Collections
    • ADA Standards of Medical Care
  • Browse
    • By Topic
    • Issue Archive
    • Saved Searches
    • Special Article Collections
    • ADA Standards of Medical Care
  • Info
    • About the Journal
    • About the Editors
    • ADA Journal Policies
    • Instructions for Authors
    • Guidance for Reviewers
  • Reprints/Reuse
  • Advertising
  • Subscriptions
    • Individual Subscriptions
    • Institutional Subscriptions and Site Licenses
    • Access Institutional Usage Reports
    • Purchase Single Issues
  • Alerts
    • E­mail Alerts
    • RSS Feeds
  • Podcasts
    • Diabetes Core Update
    • Special Podcast Series: Therapeutic Inertia
    • Special Podcast Series: Influenza Podcasts
    • Special Podcast Series: SGLT2 Inhibitors
    • Special Podcast Series: COVID-19
  • Submit
    • Submit a Manuscript
    • Journal Policies
    • Instructions for Authors
    • ADA Peer Review
Original Research
Periodontal Disease and Incident Type 2 Diabetes Mellitus: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-up Study
Ryan T. Demmer, David R. Jacobs, Moïse Desvarieux
Diabetes Care 2008 Apr; https://doi.org/10.2337/dc08-0026
Next
  • Article
  • Suppl Material
  • Info & Metrics
  • PDF
Loading

Abstract

Objective: Type 2 Diabetes Mellitus (diabetes) and periodontal disease are known to be associated but the temporality of this relationship has not been firmly established. We investigated whether baseline periodontal disease independently predicts incident diabetes over two decades of follow-up.

Research Design and Methods: 9,296 nondiabetic male and female National Health and Nutrition Examination Survey (NHANES I) participants aged 25-74 years who completed a baseline dental examination (1971–1976) and at least one follow-up evaluation (1982–1992) were studied. We defined 6 categories of baseline periodontal disease using the periodontal index (PI). Of 7,168 dentate participants, 47% had PI=0 (“periodontally health”); the remaining were classified into PI quintiles. Incident diabetes was defined by: i) death certificate (ICD-9 code 250); ii) self-report diabetes requiring pharmacological treatment; or iii) healthcare facility stay with diabetes discharge code. Multivariable logistic regression models assessed incident diabetes odds across increasing levels of PI in comparison to periodontally healthy participants.

Results: The adjusted odds ratios (OR) for incident diabetes in periodontal index categories 1 and 2 were not elevated while the OR in periodontal index categories 3 through 5 were: 2.26 (95%CI:1.56,3.27), 1.71 (95%CI:1.09,2.69) and 1.50 (95%CI:0.99,2.27), respectively. OR in edentulous was 1.30(95%CI:1.00, 1.70). Dentate participants with advanced tooth loss realized an OR=1.70(p<0.05) relative to those with minimal tooth loss.

Conclusions: Baseline periodontal disease is an independent predictor of incident diabetes in the nationally representative sample of NHANES I.

Footnotes

    • Received January 12, 2008.
    • Accepted March 31, 2008.
  • Copyright © American Diabetes Association
Next
Back to top
Diabetes Care: 44 (4)

Current Issue

April 2021
Volume 44, Issue 4

  • Current Issue
  • Index by Author
  • Issue Archive
  • Podcasts
Sign up to receive current issue alerts
View Selected Citations (0)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about Diabetes Care.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Periodontal Disease and Incident Type 2 Diabetes Mellitus: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-up Study
(Your Name) has forwarded a page to you from Diabetes Care
(Your Name) thought you would like to see this page from the Diabetes Care web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Periodontal Disease and Incident Type 2 Diabetes Mellitus: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-up Study
Ryan T. Demmer, David R. Jacobs, Moïse Desvarieux
Diabetes Care Apr 2008, DOI: 10.2337/dc08-0026

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Add to Selected Citations
Share

Periodontal Disease and Incident Type 2 Diabetes Mellitus: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-up Study
Ryan T. Demmer, David R. Jacobs, Moïse Desvarieux
Diabetes Care Apr 2008, DOI: 10.2337/dc08-0026
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Suppl Material
  • Info & Metrics
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • ACE I/D Polymorphism, Plasma ACE Levels, and Long-term Kidney Outcomes or All-Cause Death in Patients With Type 1 Diabetes
  • Associations Between Exposure to Gestational Diabetes Mellitus In Utero and Daily Energy Intake, Brain Responses to Food Cues, and Adiposity in Children
  • Efficacy and Safety of Mulberry Twig Alkaloids Tablet for the Treatment of Type 2 Diabetes: A Multicenter, Randomized, Double-Blind, Double-Dummy, and Parallel Controlled Clinical Trial
Show more Original Research

Similar Articles

Navigate

  • Current Issue
  • Standards of Care Guidelines
  • Online Ahead of Print
  • Archives
  • Submit
  • Subscribe
  • Email Alerts
  • RSS Feeds

More Information

  • About the Journal
  • Instructions for Authors
  • Journal Policies
  • Reprints and Permissions
  • Advertising
  • Privacy Policy: ADA Journals
  • Copyright Notice/Public Access Policy
  • Contact Us

Other ADA Resources

  • Diabetes
  • Clinical Diabetes
  • Diabetes Spectrum
  • Scientific Sessions Abstracts
  • Standards of Medical Care in Diabetes
  • BMJ Open - Diabetes Research & Care
  • Professional Books
  • Diabetes Forecast

 

  • DiabetesJournals.org
  • Diabetes Core Update
  • ADA's DiabetesPro
  • ADA Member Directory
  • Diabetes.org

© 2021 by the American Diabetes Association. Diabetes Care Print ISSN: 0149-5992, Online ISSN: 1935-5548.