RT Journal Article SR Electronic T1 Explaining the Increase of Diabetes Prevalence and Plasma Glucose in Mauritius JF Diabetes Care JO Diabetes Care FD American Diabetes Association SP 87 OP 91 DO 10.2337/dc11-0886 VO 35 IS 1 A1 Magliano, Dianna J. A1 Söderberg, Stefan A1 Zimmet, Paul Z. A1 Chen, Lei A1 Joonas, Noorjehan A1 Kowlessur, Sudhir A1 Larhubarbe, Jose A1 Gaoneadry, Dhanunjaye A1 Pauvaday, Vassen A1 Tuomilehto, Jaakko A1 Alberti, K. George M.M. A1 Shaw, Jonathan E. YR 2012 UL http://care.diabetesjournals.org/content/35/1/87.abstract AB OBJECTIVE Secular trends in the epidemiology of diabetes are best described by studying the same population over time, but few such studies exist. Using surveys from Mauritius in 1987 and 2009, we examined 1) the change in the prevalence of diabetes, 2) the extent to which changes in traditional diabetes risk factors explained the increase, and 3) the change in the distribution of plasma glucose levels over time.RESEARCH DESIGN AND METHODS Independent population-based surveys were undertaken in Mauritius in 1987 and 2009 using similar methodology in adults aged 20–74 years. Physical measurements and fasting blood samples were taken, and an oral glucose tolerance test was performed at both surveys.RESULTS The age-standardized prevalence of diabetes in 2009 was 22.3% (95% CI 20.0–24.6) among men and 20.2% (18.3–22.3) among women, representing an increase since 1987 of 64 and 62% among men and women, respectively. Concurrent changes in the distribution of age, ethnicity, waist circumference, BMI, physical activity, smoking, family history of diabetes, and hypertension explained more of the increase in the prevalence of diabetes in men than in women. Increases in plasma glucose (especially fasting glucose) were seen across the population but were greater at the upper levels.CONCLUSIONS In Mauritius, there has been a marked increase in diabetes prevalence over 22 years. This mainly results from changes in traditional risk factors, leading to population-wide increases in plasma glucose levels. Interventions to control this escalation of diabetes should focus on population-wide strategies.