RT Journal Article SR Electronic T1 Sustained Effects of a Mindfulness-Based Stress-Reduction Intervention in Type 2 Diabetic Patients JF Diabetes Care JO Diabetes Care FD American Diabetes Association SP 945 OP 947 DO 10.2337/dc11-1343 VO 35 IS 5 A1 Hartmann, Mechthild A1 Kopf, Stefan A1 Kircher, Claudia A1 Faude-Lang, Verena A1 Djuric, Zdenka A1 Augstein, Florian A1 Friederich, Hans-Christoph A1 Kieser, Meinhard A1 Bierhaus, Angelika A1 Humpert, Per M. A1 Herzog, Wolfgang A1 Nawroth, Peter P. YR 2012 UL http://care.diabetesjournals.org/content/35/5/945.abstract AB OBJECTIVE To determine whether a mindfulness-based stress reduction (MBSR) intervention is effective for reducing psychosocial distress (i.e., depression, psychosocial stress) and the progression of nephropathy (i.e., albuminuria) and for improving the subjective health status of patients with type 2 diabetes.RESEARCH DESIGN AND METHODS Patients with type 2 diabetes and microalbuminuria were randomized to a mindfulness-based intervention (n = 53) or a treatment-as-usual control (n = 57) group. The study is designed to investigate long-term outcomes over a period of 5 years. We present data up to the first year of follow-up (FU).RESULTS At FU, the MBSR group showed lower levels of depression (d = 0.71) and improved health status (d = 0.54) compared with the control group. No significant differences in albuminuria were found. Per-protocol analysis also showed higher stress reduction in the intervention group (d = 0.64).CONCLUSIONS MBSR intervention achieved a prolonged reduction in psychosocial distress. The effects on albuminuria will be followed up further.