Sex | Baseline–Year 1 | Years 1, 2, and 3 | Years 3, 4, 5, and 6 | Years 6, 7, 8, and 9 | P value† |
---|---|---|---|---|---|

Female | |||||

Conventional | |||||

Predicted | 0.2974 | 0.1512 | 0.1589 | 0.1681 | |

Observed | 0.3685 | 0.2228 | 0.1579 | 0.2495 | |

n | 278 | 276 | 226 | 67 | |

Intensive | |||||

Predicted | 0.9925 | 0.4267 | 0.3999 | 0.3677 | 0.0005 |

Observed | 1.1103 | 0.4892 | 0.3080 | 0.3325 | |

n | 301 | 298 | 246 | 73 | |

P value for difference between groups | 0.0001 | 0.0002 | 0.0058 | 0.3870 | |

Male | |||||

Conventional | |||||

Predicted | 0.3903 | 0.1316 | 0.1148 | 0.0946 | |

Observed | 0.4026 | 0.1511 | 0.1402 | 0.1324 | |

n | 347 | 347 | 280 | 76 | |

Intensive | |||||

Predicted | 1.1335 | 0.3797 | 0.2940 | 0.1913 | <0.0001 |

Observed | 1.0926 | 0.4575 | 0.3172 | 0.2323 | |

n | 316 | 314 | 256 | 73 | |

P value for difference between groups | <0.0001 | <0.0001 | 0.0082 | 0.3573 |

- *
↵* The upper figure of each pair is the average annual change in BMI predicted by the growth-curve model during the interval in question. The lower figure is the observed average rate of change for the same period.

*P*values for the treatment-group difference in observed rates of change are from the Wilcoxon’s rank-sum test (baseline–year 1) or the Wei-Lachin test of stochastic ordering, applied separately for all other periods. - †
↵†

*P*value for test of trends over time, based on observed rates, between treatment groups within sex.