Table 4—

Body composition characteristics associated with major weight gain

CharacteristicMajor weight gainTreatment groupnFirst quartileMedianThird quartileAdjusted mean*P value for treatment groupP value for weight gain
Percent body fat
 MenYesINT3824.527.131.725.9<0.0001
CON523.024.728.724.30.3733
NoINT26015.119.222.717.80.1479
CON33214.718.423.217.20.0076
 Women§YesINT6736.838.941.639.8<0.0001
CON936.338.140.840.10.5958
NoINT22027.030.734.032.30.2342
CON24926.830.333.931.9<0.0001
Fat-free mass (kg)
 MenYesINT3865.869.478.568.8<0.0001
CON567.667.973.766.90.7189
NoINT26060.465.370.663.2<0.0001
CON33260.364.870.961.60.0131
 WomenYesINT6747.853.356.554.9<0.0001
CON947.450.954.853.80.2537
NoINT22043.145.749.551.00.0019
CON24942.445.348.750.10.0005
  • *

    * Least-squares estimates of cell means after adjusting for covariance with weight at baseline;

  • from the Wilcoxon’s test of differences between treatment groups within weight-gain categories after adjusting for covariance with weight at baseline;

  • from the Wilcoxon’s test of differences between patients with and without major weight gain within treatment groups after adjusting for covariance with weight at baseline;

  • §

    § includes all women randomized as adults. Excluding women who became pregnant during the trial yields substantially identical results. INT, intensive; CON, conventional.