Table 1

Plasma substrate concentrations during insulin clamp

ControlLipidSalsalate + lipid
Basal120 minBasal120 minBasal120 min
Plasma glucose (mmol/L)5.1 ± 0.14.4 ± 0.1*5.1 ± 0.14.4 ± 0.1*5.0 ± 0.14.5 ± 0.1*
Insulin (pmol/L)29 ± 5327 ± 22**48 ± 8#396 ± 77**74 ± 15##466 ± 43**
FFA (mEq/L)0.7 ± 0.10.2 ± 0.1**4.2 ± 0.4#2.9 ± 0.3**3.2 ± 0.3#&2.4 ± 0.3***
  • *P < 0.0001, **P < 0.001, ***P = 0.001 vs. respective basal;

  • #P < 0.001, ##P < 0.005 vs. control basal;

  • &P < 0.04 vs. lipid control.