Table 2

LDR and ST predict incident retinopathy in prospective GEE univariate and multivariate models

VariablenPts (n)UnivariateMultivariate 1*Multivariate 2
OR (95% CI)POR (95% CI)POR (95% CI)P
LDRa736287
Quartile
 1 (<19.8)184921.9 (1.3–2.7)0.0011.8 (1.2–2.7)0.0031.8 (1.2–2.6)0.003
 2 (19.8–65.6)184681.3 (0.9–1.9)0.21.3 (0.9–2.0)0.21.3 (0.9–2.0)0.2
 3 (65.6–114.2)184711.2 (0.8–1.8)0.31.3 (0.9–2.0)0.21.3 (0.9–1.9)0.2
 4 (>114.2)18456ReferenceReferenceReference
STa736287
Quartile
 1 (<1,091)18466ReferenceReferenceReference
 2 (1,091–1,107)184761.5 (1.0–2.2)0.031.6 (1.1–2.4)0.021.6 (1.1–2.3)0.02
 3 (1,108–1,127)184691.5 (1.1–2.2)0.031.5 (1.0–2.2)0.031.6 (1.1–2.4)0.02
 4 (>1,127)184761.6 (1.1–2.3)0.0081.6 (1.1–2.4)0.021.5 (1.0–2.2)0.03
  • Pts, patients.

  • *Model 1 adjusted for age, sex, and diabetes duration.

  • †Model 2 adjusted for model 1 covariates plus A1C, DBP, BMI, total cholesterol, and relevant interactions (sex*A1C and sex*cholesterol).