Main clinical and biochemical characteristics of type 2 diabetic patients and control subjects
| Diabetic patients | Control subjects | P | |
|---|---|---|---|
| Sex (M/F) | 30/6 | 5/2 | NS |
| Age (years) | 55 ± 6.0 (44–67) | 52 ± 4.0 (47–60) | NS |
| Weight (kg) | 75 ± 10 (52–96) | 67 ± 8.0 (59–80) | <0.05 |
| BMI (kg/m2) | 26.5 ± 2.5 (20–29.8) | 24.5 ± 2.1 (22–28) | <0.05 |
| TBF (kg) | 22 ± 6.0 (9–35) | 19 ± 4.0 (6–25) | <0.05 |
| FFM (kg) | 53 ± 7.0 (34–67) | 48 ± 9.0 (35–58) | <0.05 |
| Waist girth (cm) | 96 ± 7.0 (81–111) | 84 ± 9.0 (74–91) | <0.05 |
| WHR | 0.97 ± 0.05 (0.83–1.05) | 0.81 ± 0.11 (0.68–0.89) | <0.01 |
| Systolic BP (mmHg) | 148 ± 19 (105–187) | 121 ± 13 (105–135) | <0.01 |
| Diastolic BP (mmHg) | 91 ± 12 (68–114) | 79 ± 6.0 (65–88) | <0.01 |
| Fasting insulin (pmol/l) | 70 ± 7.0 (35–110) | 40 ± 5.0 (10–49) | <0.01 |
| Fasting glucose (mmol/l) | 10.3 ± 2 (7–16.5) | 5.1 ± 1.0 (4.8–6.0) | <0.01 |
| HbA1c (%) | 6.7 ± 1.2 (4.2–9.0) | ND | ND |
| LDL cholesterol (mmol/l) | 3.7 ± 1.1 (1.6–6.9) | 3.2 ± 0.5 (1.4–5.7) | NS |
| HDL cholesterol (mmol/l) | 1.07 ± 0.41 (0.4–1.8) | 1.23 ± 0.15 (0.7–2.1) | NS |
| Triglycerides (mmol/l) | 2.2 ± 1.12 (0.6–5.3) | 1.6 ± 0.51 (0.5–2.9) | NS |
| ICAM-1 (ng/ml) | 278 ± 81 (159–473) | 266 ± 74 (155–396) | NS |
| VCAM-1 (ng/ml) | 630 ± 175 (375–1,103) | 551 ± 109 (452–782) | NS |
| E-selectin (ng/ml) | 42 ± 20 (12–114) | 48 ± 31 (18–109) | NS |
| P-selectin (ng/ml) | 89 ± 61 (28–326) | 99 ± 30 (73–160) | NS |
| TGD during clamp (μmol · min−1 · kg FFM−1) | 22 ± 11 (8.0–61) | 53 ± 13 (35–76) | <0.01 |
Data are means ± SD (range). BP, blood pressure; FFM, fat-free mass; ND, not determined; NS, not significant.