Table 1—

Main clinical and biochemical characteristics of type 2 diabetic patients and control subjects

Diabetic patientsControl subjectsP
Sex (M/F)30/65/2NS
Age (years)55 ± 6.0 (44–67)52 ± 4.0 (47–60)NS
Weight (kg)75 ± 10 (52–96)67 ± 8.0 (59–80)<0.05
BMI (kg/m2)26.5 ± 2.5 (20–29.8)24.5 ± 2.1 (22–28)<0.05
TBF (kg)22 ± 6.0 (9–35)19 ± 4.0 (6–25)<0.05
FFM (kg)53 ± 7.0 (34–67)48 ± 9.0 (35–58)<0.05
Waist girth (cm)96 ± 7.0 (81–111)84 ± 9.0 (74–91)<0.05
WHR0.97 ± 0.05 (0.83–1.05)0.81 ± 0.11 (0.68–0.89)<0.01
Systolic BP (mmHg)148 ± 19 (105–187)121 ± 13 (105–135)<0.01
Diastolic BP (mmHg)91 ± 12 (68–114)79 ± 6.0 (65–88)<0.01
Fasting insulin (pmol/l)70 ± 7.0 (35–110)40 ± 5.0 (10–49)<0.01
Fasting glucose (mmol/l)10.3 ± 2 (7–16.5)5.1 ± 1.0 (4.8–6.0)<0.01
HbA1c (%)6.7 ± 1.2 (4.2–9.0)NDND
LDL cholesterol (mmol/l)3.7 ± 1.1 (1.6–6.9)3.2 ± 0.5 (1.4–5.7)NS
HDL cholesterol (mmol/l)1.07 ± 0.41 (0.4–1.8)1.23 ± 0.15 (0.7–2.1)NS
Triglycerides (mmol/l)2.2 ± 1.12 (0.6–5.3)1.6 ± 0.51 (0.5–2.9)NS
ICAM-1 (ng/ml)278 ± 81 (159–473)266 ± 74 (155–396)NS
VCAM-1 (ng/ml)630 ± 175 (375–1,103)551 ± 109 (452–782)NS
E-selectin (ng/ml)42 ± 20 (12–114)48 ± 31 (18–109)NS
P-selectin (ng/ml)89 ± 61 (28–326)99 ± 30 (73–160)NS
TGD during clamp (μmol · min−1 · kg FFM−1)22 ± 11 (8.0–61)53 ± 13 (35–76)<0.01
  • Data are means ± SD (range). BP, blood pressure; FFM, fat-free mass; ND, not determined; NS, not significant.