Table 2

IRR for diabetes according to CES-D score categories and use of antidepressant medication in the BWHS, 1999–2011

CES-D score categoriesAntidepressant use
<1616–2223–32≥33NoYes
All BMI
 Cases/person-years2,306/261,795549/52,538339/31,365178/13,7093,079/340,419293/18,988
 IRR
  Basic multivariate*1.00 (reference)1.23 (1.12–1.35)1.26 (1.12–1.41)1.45 (1.24–1.69)1.00 (reference)1.43 (1.26–1.62)
  +Lifestyle factors1.00 (reference)1.18 (1.07–1.30)1.17 (1.04–1.32)1.31 (1.12–1.53)1.00 (reference)1.35 (1.19–1.53)
  +BMI1.00 (reference)1.11 (1.01–1.22)1.08 (0.96–1.22)1.22 (1.04–1.43)1.00 (reference)1.26 (1.11–1.43)
BMI ≥30 kg/m2
 Cases/person-years1,550/93,203380/21,932260/13,871137/6,3572,105/126,564222/8,799
 IRR1.00 (reference)1.06 (0.95–1.19)1.10 (0.96–1.26)1.24 (1.03–1.48)1.00 (reference)1.26 (1.09–1.46)
  • *Basic covariates: age, questionnaire cycle, healthcare utilization, family history of diabetes, and years of education.

  • †Lifestyle factors: vigorous activity levels, daily hours of television watching, caloric intake, smoking, and alcohol consumption.

  • ‡IRRs adjusted for all basic covariates + lifestyle factors + continuous BMI.