Table 1 —

Characteristics of the study groups

Patients with type 2 diabetes (n = 81)
Normal subjects (n = 41)
0 months3 months12 months
Age (years)58 ± 151 ± 1**
Sex (M/F)52/2928/13
Weight (kg)82.4 ± 1.783.8 ± 1.7§86.0 ± 1.8§#81.8 ± 1.8
Fat-free mass (kg)56.5 ± 1.358.4 ± 1.760.9 ± 1.8§#58.2 ± 0.9
Waist-to-hip ratio0.94 ± 0.010.94 ± 0.010.95 ± 0.010.91 ± 0.01
HbA1c(%)*9.7 ± 0.28.1 ± 0.1§7.6 ± 0.1§#5.5 ± 0.1††
Fasting plasma glucose (mmol/l)11.9 ± 0.36.8 ± 0.3§6.3 ± 0.1§5.5 ± 0.1††
Serum triglyceride level (mmol/l)2.5 ± 0.11.6 ± 0.1§1.9 ± 0.2§1.2 ± 0.05††
Serum HDL cholesterol level (mmol/l)1.1 ± 0.41.2 ± 0.041.1 ± 0.041.3 ± 0.03**
Serum LDL cholesterol level (mmol/l)3.5 ± 0.13.4 ± 0.13.4 ± 0.13.7 ± 0.07
  • Data are n or means ± SEM.

  • *

    * Reference range 4.0–6.0%.

  • P < 0.05,

  • P < 0.01,

  • §

    § P < 0.001 for 3 or 12 vs. 0 months;

  • P < 0.05,

  • P < 0.01,

  • #

    # P < 0.001 for 12 vs. 3 months;

  • **

    ** P < 0.05,

  • ‡‡

    ‡‡ P < 0.001 for patients with type 2 diabetes versus normal subjects.