Table 1

CGM measures of glycemic control and variability among Ab+ versus Ab− subjects and among Ab+ progressors versus Ab+ nonprogressors

VariablesAb+ subjects
n = 14Ab− subjects
n = 9P valueAb+ progressors
n = 5Ab+ nonprogressors
n = 9P value
Age, years13.8 ± 3.513.6 ± 2.00.8811.7 ± 2.314.9 ± 3.60.08
Mean glucose, mg/dL117 ± 13109 ± 110.07125 ± 16112 ± 80.19
Mean day glucose, mg/dL119 ± 13109 ± 110.06129 ± 15114 ± 80.06
Mean night glucose, mg/dL111 ± 16111 ± 150.98115 ± 22109 ± 120.52
Maximum day glucose value, mg/dL221 ± 53168 ± 310.011241 ± 38210 ± 580.44
Maximum night glucose value, mg/dL173 ± 35170 ± 440.57185 ± 34166 ± 360.36
SD, mg/dL26 ± 819 ± 70.03932 ± 723 ± 70.06
CV, mg/dL22 ± 617 ± 50.04626 ± 520 ± 60.15
Range, mg/dL166 ± 53111 ± 430.016182 ± 37157 ± 600.3
% Time ≥140 mg/dL0.18 ± 0.150.09 ± 0.090.040.31 ± 0.180.12 ± 0.070.04
% Time ≥200 mg/dL0.02 ± 0.030 ± 0.010.0750.03 ± 0.040.01 ± 0.010.06
AUC, mg/min/dL676,196 ± 72,197627,443 ± 64,8230.16725,629 ± 91,052648,733 ± 44,1490.15
AUC day, mg/min/dL514,433 ± 54,758466,436 ± 48,5770.06561,040 ± 61,792488,540 ± 29,1800.02
AUC night, mg/min/dL160,977 ± 22,912158,913 ± 22,3080.60164,180 ± 32,128159,198 ± 18,0820.52
HbA1c, % (mmol/mol)5.5 ± 0.8 (37 ± 8.7)NANA5.9 ± 0.3 (41 ± 3.3)5.3 ± 0.9 (34 ± 9.8)0.16
  • Values are mean ± SD. NA, HbA1c not done in Ab− subjects.

  • †Day values are between 6:00 a.m. and midnight.

  • ‡AUC calculated by the trapezoidal rule.