Table 2 —

Estimates of β-cell function based on availability of sampling time points in nondiabetic subjects

Sampling timesEstimated first phase (pmol/l)Estimated second phase (pmol/l)
0 and 120 min2,503 + 6.476 × Ins0 − 126.5 × Gluc120 + 0.954 × Ins120 − 239.3 × Gluco393 + 1.163 × Ins0 − 40.72 × Gluc120 + 0.313 × Ins120
r = 0.65r = 0.70
0, 60, and 120 min1,194 + 4.724 × Ins0 − 117.0 × Gluc60 + 1.414 × Ins60295 + 0.349 × Ins60 − 25.72 × Gluc60 + 1.107 × Ins0
r = 0.71r = 0.75
0 and 30 min1,283 + 1.829 × Ins30 − 138.7 × Gluc30 + 3.772 × Ins0286 + 0.416 × Ins30 − 25.94 × Gluc30 + 0.926 × Ins0
r = 0.78r = 0.79
0, 30, and 60 min1,283 + 1.829 × Ins30 − 138.7 × Gluc30 + 3.772 × Ins0286 + 0.416 × Ins30 − 25.94 × Gluc30 + 0.926 × Ins0
r = 0.78r = 0.79
0 and 120 min*2,032 + 4.681 × Ins0 − 135.0 × Gluc120 + 0.995 × Ins120 + 27.99 × BMI − 269.1 × Gluc0277 + 0.800 × Ins0 − 42.79 × Gluc120 + 0.321 × Ins120 + 5.338 × BMI r = 0.73
r = 0.68
0, 60, and 120 min*728 + 3.537 × Ins0 − 120.3 × Gluc60 + 1.341 × Ins60 + 21.27 × BMI208 + 0.335 × Ins60 − 26.33 × Gluc60 + 0.887 × Ins0 + 3.933 × BMI
r = 0.73r = 0.76
0 and 30 min*1,283 + 1.829 × Ins30 − 138.7 × Gluc30 + 3.772 × Ins0286 + 0.416 × Ins30 − 25.94 × Gluc30 + 0.926 × Ins0
r = 0.78r = 0.79
0, 30, and 60 min*1,283 + 1.829 × Ins30 − 138.7 × Gluc30 + 3.772 × Ins0286 + 0.416 × Ins30 − 25.94 × Gluc30 + 0.926 × Ins0
r = 0.78r = 0.79
  • Insulin (Ins) measured in picomoles per liter; glucose (Gluc) measured in millimoles per liter.

  • *

    * Inclusion of demographic parameters (age, sex, BMI, and waist-to-hip ratio) in model. All P values < 0.001.