Table 1 —

Estimates of insulin sensitivity based on availability of sampling time points in nondiabetic subjects

Sampling timesEstimated insulin sensitivity index (μmol · kg–1 · min–1 · pmol/l)Estimated metabolic clearance rate (ml · kg–1 · min–1)
0 and 120 min0.156 − 0.0000459 × Ins120 − 0.000321 × Ins0 − 0.00541 × Gluc12013.273 − 0.00384 × Ins120 − 0.0232 × Ins0 − 0.463 × Gluc120
r = 0.69r = 0.68
0, 60, and 120 min0.156 − 0.0000459 × Ins120 − 0.000321 × Ins0 − 0.00541 × Gluc12013.273 − 0.00384 × Ins120 − 0.0232 × Ins0 − 0.463 × Gluc120
r = 0.69r = 0.68
0 and 30 min0.205 − 0.000437 × Ins0 − 0.0185 × Gluc015.841 − 0.0341 × Ins0 − 1.262 × Gluc0
r = 0.62r = 0.59
0, 30, and 60 min0.149 − 0.000467 × Ins0 − 0.00466 × Gluc6012.464 − 0.0357 × Ins0 − 0.376 × Gluc60
r = 0.65r = 0.62
0 and 120 min*0.222 − 0.00333 × BMI − 0.0000779 × Ins120 − 0.000422 × Age19.240 − 0.281 × BMI − 0.00498 × Ins120 − 0.333 × Gluc120
r = 0.79r = 0.79
0, 60, and 120 min*0.222 − 0.00333 × BMI − 0.0000779 × Ins120 − 0.000422 × Age19.240 − 0.281 × BMI − 0.00498 × Ins120 − 0.333 × Gluc120
r = 0.79r = 0.79
0 and 30 min*0.213 − 0.00305 × BMI − 0.000308 × Ins0 − 0.000640 × Age18.078 − 0.267 × BMI − 0.0214 × Ins0 − 0.0501 × Age
r = 0.75r = 0.75
0, 30, and 60 min*0.231 − 0.00296 × BMI − 0.000284 × Ins0 − 0.000506 × Age − 0.00318 × Gluc6019.487 − 0.260 × BMI − 0.254 × Gluc60 − 0.0195 × Ins0 − 0.0394 × Age
r = 0.78r = 0.77
  • Insulin (Ins) measured in picomoles per liter; glucose (Gluc) measured in millimoles per liter.

  • *

    * Inclusion of demographic parameters (age, sex, BMI, and waist-to-hip ratio) in model. All P values < 0.001.