Table 2 —

Measured and derived variables

Sea level
High altitude
PregnantNonpregnantPregnantNonpregnant
n123319222
Glucose (mmol/l)4.66* (0.44)5.33* (0.61)4.39* (0.56)4.97* (0.56)
Insulin (pmol/l)43.8* (34.80)53.4* (29.4)31.5* (16.35)35.1* (28.8)
Proinsulin (pmol/l)6.60* (5.30)6.00 (7.60)3.55* (4.88)6.55 (7.28)
C-peptide (nmol/l)0.43 (0.25)0.40 (0.20)0.40 (0.18)0.46 (0.26)
Insulin sensitivity (%)121.0* (96.9)97.4* (56.1)166.9* (80.0)148.5* (129.3)
β-cell function (%)97.3 (53.5)84.5* (23.0)90.2 (38.7)73.3* (39.4)
C-peptide–to–insulin ratio9.11* (4.27)7.98* (1.70)11.95* (5.45)13.72* (6.76)
  • Data are median (interquartile range).

  • *

    * P < 0.05 for the difference between sea level and high altitude;

  • P < 0.05 for the difference between pregnant and nonpregnant groups.