Table 2 —

Patterns of body fat distribution and indexes of insulin secretion and resistance of subjects

VariableControl subjects (n = 52)Offspring of diabetic patients
NGT (n = 52)IGT (n = 21)Diabetes (n = 9)
Fat mass (kg)17.6 ± 1.316.9 ± 0.616.9 ± 1.118.3 ± 1.2
Percent body fat (%)27.9 ± 1.326.7 ± 0.625.5 ± 1.226.6 ± 1.2
Visceral fat area (cm2)61.9 ± 8.575.0 ± 4.787.8 ± 9.1132.8 ± 13.5*
Visceral-to-subcutaneous ratio0.40 ± 0.10.49 ± 0.00.57 ± 0.10.73 ± 0.0*
Leptin (ng/ml)5.8 ± 1.27.1 ± 1.18.2 ± 2.07.1 ± 0.8
SI (× 10−4 min−1/[μU/ml])5.88 ± 0.65.04 ± 0.64.98 ± 1.22.04 ± 0.6*
SG (10−2/min)2.29 ± 0.02.18 ± 0.01.94 ± 0.02.52 ± 0.1
AIR (μU/ml)53.2 ± 7.738.5 ± 5.026.3 ± 5.84.9 ± 2.6*
  • Values are means ± SEM.

  • *

    * P < 0.05 versus control, NGT, and IGT;

  • P < 0.05 versus control and NGT;

  • P < 0.05 versus control.