Table 3 —

Incidence of most common adverse events

PlaceboMIGMETMIG + MET
n83828376
Any adverse events71 (85.5)79 (96.3)78 (94.0)74 (97.4)
Digestive system
 Any event29 (34.9)58 (70.7)50 (60.2)66 (86.8)
 Flatulence12 (14.5)46 (56.1)24 (28.9)48 (63.2)
 Diarrhea9 (10.8)35 (42.7)23 (27.7)42 (53.3)
 Constipation5 (6.0)5 (6.1)7 (8.4)7 (9.2)
 Nausea2 (2.4)7 (8.5)14 (16.9)13 (17.1)
 Dyspepsia2 (2.4)6 (7.3)7 (8.4)11 (14.5)
 Abdominal cramps2 (2.4)4 (4.9)5 (6.0)6 (7.9)
Hypoglycemia7 (8.4)7 (8.5)8 (9.6)10 (13.2)
  • Data are n (%). Common adverse events are considered those with incidence >7% in at least one treatment group. MIG, miglitol, MET, metformin.