Table 2 —

Hemochromatosis C282Y and H63D polymorphisms in patients with type 2 diabetes and control subjects

Control subjectsType 2 diabetic patients
C282Y
 All196  563
 CC193 (98)520 (92)
 CY and YY 3 (2)  43 (7)*
 OR (95% CI)Reference5.3 (1.6–17.3)
 Allele C3891,082
 Allele Y 3  44
H63D
 All196  563
 HH149 (76)385 (68)
 HD and DD 47 (24)178 (32)
 OR (95% CI)§Reference1.5 (1.0–2.1)
 Allele H342  928
 Allele D 50  198
  • Data are n (%), unless otherwise indicated.

  • *

    * One subject was TT homozygote;

  • χ2 = 8.48, P = 0.0036, type 2 diabetic patients vs. control subjects;

  • χ2 = 8.55, P = 0.0035, allele C vs. allele Y;

  • §

    § χ2 = 3.71, P = 0.0542, type 2 diabetic patients vs. control subjects;

  • χ2 = 4.61, P = 0.0317, allele H vs. allele D.