Table 3 —

Hemochromatosis 282Y and H63D polymorphisms in patients with type 2 diabetes according to renal status

Normoalbuminuria*Nephropathy
282Y
 All162262
 CC152 (94)237 (90)
 CY and YY 10 (6)  25 (10)
 OR (95% CI)Reference1.6 (0.7–3.4)
 Allele C§313499
 Allele Y 11 25
H63D
 All162262
 HH122 (75)165 (63)
 HD and DD 40 (25) 97 (37)
 OR (95% CI)Reference1.8 (1.2–2.8)
 Allele H278417
 Allele D 46107
  • Data are n (%), unless otherwise indicated.

  • *

    * Only patients with duration of type 2 diabetes ≥10 years after diagnosis;

  • nephropathy means microalbuminuria or proteinuria;

  • χ2 = 1.09, P = 0.2968, normoalbuminuria vs. nephropathy;

  • §

    § χ2 = 0.62, P = 0.4293, allele C vs. allele Y;

  • χ2 = 6.4, P = 0.011, normoalbuminuria vs. nephropathy;

  • χ2 = 4.83, P = 0.0280, allele C vs. allele Y.