Table 3—

Effect of diabetes on long-term mortality after acute myocardial infarction in recent studies

Studyn (Diabetic)Follow-upRRAdjustedEarly DeathsComments
Sahlgrenska (1993)15858 (97)1 year1.6NoExcludedAdjusted RR NS
TAMI (1993)141,071 (148)∼3 yearsNSYesIncluded
GISSI-2 (1993)611,667 (1838)6 months0.7–7.3YesExcludedInsulin Rx worse only in women
TIMI-II (1993)112,173 (294)3 years2.25NoIncluded
ITPA/SMT (1993)58,055 (883)6 months1.74YesExcludedInsulin Rx same as other Rx
MIDAS (1994)1242,595 (9695)3 years1.15–1.84YesExcludedLower RR with higher age
GUSTO-1 (1997)441,021 (5944)1 year1.6NoExcludedAdjusted RR significant; insulin Rx worse than other Rx
SPRINT (1997)75,839 (624)10 years1.32–2.59YesIncludedInsulin Rx worse than other Rx
FINMONICA (1998)94,065 (620)1 year1.97/4.17 Men/WomenYesExcluded
ISIS-2 (1998)1317,187 (1289)10 years1.55NoIncluded
Augsburg (2000)182,210 (468)5 years1.64YesExcluded
CCP (2001)10117,599 (36,767)1 year1.26–1.48YesIncludedInsulin Rx worse than other Rx
  • Data are n unless otherwise indicated. Superscript numbers indicate reference numbers for individual studies. NS, not statistically significant; RR, relative risk; Rx, therapy.