Table 1—

Annual cardiovascular drug use and hospitalizations from 1 year before until 6 years after the initiation of oral antidiabetic therapy comparing patients with type 2 diabetes (DM) and nondiabetic subjects (Non-DM)

YearsCardiovascular drug use
Cardiovascular hospitalizations
nDM (%)Non-DM (%)AR [95% CI]DM (%)Non-DM (%)AR [95% CI]
*2,58456.141.226.6 (22.2–30.7)5.02.353.1 (37.8–66.0)
12,58460.344.925.5 (21.5–29.4)4.72.547.5 (28.4–60.5)
22,08863.247.425.0 (20.7–29.1)5.43.535.4 (13.6–51.4)
31,52663.147.125.4 (20.3–30.1)4.32.932.2 (1.9–53.6)
498064.248.624.3 (18.0–30.1)4.63.133.3 (−5.8 to 57.1)
557961.148.720.3 (11.4–28.3)3.62.433.3 (−30.1 to 65.9)
624958.248.616.5 (1.5–29.2)3.24.0−25.0 (−212.1 to 49.9)
1–62,58473.857.522.1 (18.9–25.2)15.410.035.1 (24.8–43.9)
  • *

    * The first year before the start of oral antidiabetic therapy;

  • average prevalence of years 1–6 calculated per subject.