Table 4—

Significant predictors of amputation during the follow-up period (Cox’s regression analysis)

VariableNumber of cases (number of amputations)Levels of variablesUnivariate RR (95% CI)Univariate PMultivariate RR (95% CI), P (number of cases/ulcers)
Previous ulcer169 (19)No (n = 120)1.000.004NA
Yes (n = 49)3.79 (1.52–9.42)
PPT (foot-dorsum)168 (19)4,5 (≤10 g, n = 148)1.000.005
6,7 (>10 g, n=20)4.06 (1.54–10.69)
PPT (foot-plantar)168 (19)4,5 (≤10 g, n = 115)1.00<0.0015.18 (1.96–13.68)
5,7 (>10 g, n = 53)5.34 (2.03–14.05)P = 0.001, (166/19)
VPT (Hallux)166 (19)1.05 (1.01–1.08)0.011
MNCV130 (10)0.86 (0.76–0.97)0.015
TPT167 (19)1.11 (1.00–1.24)0.049
Calcification166 (19)No (n = 139)1.000.0112.88 (1.13–7.35)
Yes (n = 27)3.37 (1.33–8.57)P = 0.027, (166/19)
  • Data analyzed as continuous variables except where stated. Significant predictors only shown (P < 0.05). Previous ulcer was removed from multivariate analysis as a confounding variable.