Table 5—

Significant predictors of death during the follow-up period (Cox’s regression analysis)

VariableNumber of cases (number of deaths)Levels of variablesUnivariate RR (95% CI)Univarate PMultivariate RR (95% CI) P (number of cases/ulcers)
Previous ulcer169 (30)No (n = 120)1.000.021NA
Yes (n = 49)2.33 (1.14–4.77)
Creatinine128 (24)1.003 (1.002–1.005)<0.0011.01 (1.00–1.01)
P < 0.001, (91/11)
PPT (foot-dorsum)168 (29)4,5 (≤10 g, n = 148)1.000.001
6,7 (>10 g, n = 20)3.82 (1.74–8.40)
PPT (foot-plantar)168 (29)4,5 (≤10 g, n = 115)1.000.012
6,7 (>10 g, n = 53)2.54 (1.23–5.26)
VPT (Hallux)166 (29)1.05 (1.02–1.08)<0.001
MNCV130 (16)0.87 (0.79–0.95)0.0020.84 (0.73–0.97)
P = 0.016 (91/11)
TPT167 (29)1.20 (1.09–1.33)<0.001
“Calcification”166 (28)No (n = 139)1.000.013
Yes (n = 27)1.66 (1.24–6.07)
TcpO2158 (26)≥25 mmHg (n = 153)1.000.01014.32 (3.04–67.52)
<25 mmHg (n = 5)4.89 (1.46–16.36)P = 0.001 (91/11)
  • Data analyzed as continuous variables except where stated. Significant predictors only shown (P < 0.05). Previous ulcer was removed from multivariate analysis as a confounding variable.