Table 1—

Clinical and biochemical characteristics of the study groups

Control subjectsV187D carriersP
n108
Age (years)35.6 ± 1.135.3 ± 0.9NS
Sex (M/F)5/54/4NS
BMI (kg/m2)23.2 ± 0.624.0 ± 1.2NS
Fasting blood glucose (mmol/l)4.3 ± 0.24.7 ± 0.2NS
Fasting insulin (pmol/l)49.2 ± 6.642.0 ± 5.4NS
Fasting C-peptide (pmol/l)530 ± 35450 ± 51NS
Systolic blood pressure (mmHg)128 ± 4129 ± 3NS
Diastolic blood pressure (mmHg)84 ± 276 ± 2NS
HbA1c (%)5.4 ± 0.15.4 ± 0.1NS
Fasting hepatic insulin extraction (pmol C-peptide/pmol P-insulin)10.7 ± 0.310.7 ± 0.4NS
  • Data are means ± SEM or n.