Table 1—

Antihypertensive agents and their effects on adult hypertensive diabetic patients

ClassEffects on coronary events rates*Effects on progression of renal diseaseEffects on stroke
Thiazide diureticsBeneficial (A)*UnknownBeneficial (A)
Loop diureticsUnknownUnknownUnknown
Centrally acting adrenergic agentsUnknownUnknownUnknown
β-BlockersBeneficial (A)Beneficial (A)Beneficial (A)
α-BlockersControversialUnknownUnknown
DCCBsControversialControversialBeneficial (A)
NDCCBsUnknownBeneficial (C)Unknown
ACE inhibitorsBeneficial (A)Beneficial (A)Beneficial (A)
Angiotensin-2 antagonistsUnknownBeneficial (A)Unknown
  • *

    * Level of evidence for summary