Table 1—

General information of study subjects at baseline and 6 year outcomes

C (n = 22)D (n = 51)DN (n = 67)DU (n = 34)DCh (n = 17)
M/F (n)15/726/2550/1723/1111/6
Age (years)50 (46–60)53 (47–60)58 (48–62)55 (49–59)54 (48–62)
Type 1/type 2 diabetes (n)NA25/2634/3315/199/8
Duration (years)NA18 (7–25)18 (10–29)19 (12–26)20 (16–31)
Treatment = Diet/OHG/Insulin (n)NA6/13/324/21/420/13/210/4/13
BMI (kg/m2)26.5 (23.7–29.6)26.0 (23.3–28.7)26.9 (24.9–29.9)28.5 (26.0–32.0)29.8 (27.0–31.8)
HbA1c (%)5.2 (4.9–5.7)8.3 (6.7–9.2)9.4 (8.1–10.4)9.4 (8.2–10.3)10.0 (9.3–10.4)
Serum creatinine (μmol/l)100 (99–113)101 (88–112)109 (101–132)115 (96–148)121 (99–178)
History of hypertension [n (%)]5 (22.7%)13 (25.4%)33 (49.3%)13 (38.2%)4 (23.5%)
History of vascular event [n (%)]3 (13.6%)14 (27.5%)13 (19.4%)8 (23.5%)3 (17.6%)
New ulcers within 6 years (% and n for SU, RU)NA15.7 (5, 3)28.3 (12, 7)70.6 (10, 14)70.6 (6, 6)
Amputation within 6 years (% and n for MI, MA)NA3.9 (2, 0)9.0 (1, 5)26.5 (4, 5)11.8 (1, 1)
Mortality within 6 years (% and n)NA7.8 (4)16.4 (11)35.3 (12)23.5 (4)
  • Data are median (interquartile range) unless otherwise stated. SU, single ulcer; RU, recurrent ulceration; MI, minor amputation; MA, major amputation.