Table 3—

Significant predictors of new foot ulceration during the follow-up period (Cox’s regression analysis)

VariableNumber of cases (number of ulcers)Levels of variablesUnivariate RR (95% CI)Univariate PMultivariate RR (95% CI), P value (no. cases/ulcers)
Previous ulcer169 (63)No (n = 120)1.00<0.001NA
Yes (n = 49)5.81 (3.50–9.66)
BMI169 (63)1.09 (1.04–1.15)<0.001
HbA1c150 (54)1.23 (1.07–1.40)0.002
Autonomic E:I116 (43)0.004 (0.00–0.14)0.003
PPT (foot-dorsum)168 (63)4,5 (<10 g, n = 148)1.000.003
6,7 (>10 g, n = 20)2.53 (1.37–4.67)
PPT (foot-plantar)168 (63)4,5 (<10 g, n = 115)1.00<0.001
6,7 (>10 g, n = 53)4.12 (2.49–6.84)
VPT (Hallux)166 (63)1.05 (1.04–1.07)<0.001
MNCV130 (39)0.88 (0.83–0.94)<0.0010.90 (0.84–0.96)
P = 0.001, (128/39)
TPT167 (63)1.16 (1.08–1.22)<0.001
B-pressure157 (57)1.01 (1.00–1.03)0.04
  • Data analyzed as continuous variables except where stated. Significant predictors only shown (P < 0.05). B-pressure = brachial systolic blood pressure. Previous ulcer was removed from multivariate analysis as a confounding variable.