Table 3—

Mean age-adjusted values of circulating and urinary TGF-β1 and Amadori albumin by albuminuria and retinopathy

nUrinary TGF-β1/creatinine (pg/mmol)Circulating TGF-β1 (ng/ml)Amadori albumin (units/ml)
Normoalbuminuria3262.6 (2.4–2.8)5.6 (5.2–6.1)43.2 (41.8–44.6)
Microalbuminuria813.7 (3.2–4.3)6.4 (5.5–7.5)47.8 (44.9–50.6)
Macroalbuminuria1264.6 (4.1–5.2)6.2 (5.5–7.0)50.3 (48.1–52.6)
P for macro- vs. normoalbuminuria0.00010.0070.0001
P for micro- vs. normoalbuminuria0.00010.50.004
No retinopathy2352.5 (2.3–2.7)5.7 (5.2–6.2)43.5 (41.8–45.2)
Background retinopathy1463.6 (3.2–4.1)5.4 (4.8–6.1)45.2 (43.0–47.3)
Proliferative retinopathy1543.8 (3.4–4.3)6.7 (6.0–7.4)49.3 (47.2–51.4)
P for trend0.00010.020.0001
P for proliferative vs. none0.060.020.0001
P for proliferative vs. none, adjusted for AER0.90.040.04
  • Data are means (95% CI) unless otherwise indicated.