Table 2—

Responses of metabolic and hemodynamic parameters

Baseline (−30 min)After loading dose (0 min)During clamp (90 min)End of study (120 min)
Systolic BP (mmHg)
    Placebo127 ± 2128 ± 3131 ± 3133 ± 4*
    Caffeine122 ± 2129 ± 2134 ± 2134 ± 2*
Diastolic BP (mmHg)
    Placebo68 ± 268 ± 269 ± 270 ± 2
    Caffeine64 ± 170 ± 169 ± 169 ± 1*
Heart rate (bpm)
    Placebo65 ± 365 ± 368 ± 369 ± 3*
    Caffeine59 ± 259 ± 264 ± 365 ± 3*
FBF (ml · dl−1 · min−1)
    Placebo2.25 ± 0.222.17 ± 0.202.75 ± 0.313.07 ± 0.38*
    Caffeine2.26 ± 0.402.60 ± 0.363.75 ± 0.854.64 ± 1.19*
  • Data are means ± SEM.

  • *

    * P < 0.05 for trend;

  • P < 0.05 vs. baseline;

  • P < 0.05 caffeine vs. placebo for trend. BP, blood pressure.