Table 1—

Baseline characteristics of study patients

Baseline characteristicsLosartan groupPlacebo group
n1010
Sex (M/F)10/09/1
Age (years)60.6 ± 3.763.1 ± 3.9
Duration of diabetes (years)*8.5 (1–38)4.0 (1–10)
BMI (kg/m2)30.4 ± 2.128.1 ± 1.6
Serum creatinine (mmol/l)97 ± 6.592 ± 2.7
24-h urine sodium (mmol/24hr)230 ± 36210 ± 26
Clinic mean arterial blood pressure (mmHg)114 ± 3111 ± 3
AER (μg/min)26.6 ± 1.432.6 ± 1.3
HbA1c (%)7.9 ± 0.57.4 ± 0.4
Diabetes treatment
 Diet alone11
 Metformin ± sulphonylurea76
 Thiazolidinedione00
 Insulin23
  • Data are n or means ± SEM, except where otherwise noted.

  • *

    * Diabetes duration median (range);

  • AER geometric mean (tolerance factor)