Table 3—

Change in cholesterol (mg/dl) for each thiazolidinedione group, with or without concurrent HMG-CoA reductase inhibitor

1. PIO alone−5.2 ± 3.9*
2. PIO with HMG-CoA reductase inhibitor−29.4 ± 8.3atorvastatin 31
simvastatin 8
cerivastatin 1
3. ROSI alone16.8 ± 6.1
4. ROSI with HMG-CoA reductase inhibitor−4.0 ± 5.8atorvastatin 30
simvastatin 3
pravastatin 1
lovastatin 1
  • Data are means ± SEM and n. Specific concurrent HMG-CoA reductase inhibitor use and number of subjects is listed.

  • *

    * P < 0.03 vs. ROSI alone;

  • P < 0.01 vs. ROSI alone;

  • P < 0.03 vs. PIO alone and PIO with HMG-CoA reductase inhibitor.