Table 2—

Clinical features and biochemical characteristics of the patients with different renal pathologieslegend

Clinical featuresGroup I: DGS onlyGroup II: DGS with NDNGroup III: NDN onlyP
n (%)24 (35)13 (19)31 (46)
M/F (n)14/109/415/16NS
Age (years)49.0 ± 11.648.7 ± 16.548.4 ± 13.5NS
Duration of diabetes prior to biopsy (months)99.6 ± 69.7*94.3 ± 78.752.6 ± 42.00.031
Proteinuria at biopsy (median g/day)2.102.501.90NS
Proteinuria ≥2 g at biopsy (%)58.369.248.4NS
Proteinuria at follow-up (median g/day)2.602.302.00NS
SCr at biopsy (μmol/l)167 ± 105*176 ± 79140 ± 440.004
SCr ≥120 μmol/l at biopsy (%)54.2*53.819.40.014
Hypertension at biopsy (%)87.592.364.50.048
Blood pressure at follow-up (mmHg)101 ± 11111 ± 13101 ± 100.037
On ACE inhibitor (%)60.984.663.3NS
BMI at biopsy (kg/m2)24.9 ± 3.925.4 ± 9.525.6 ± 6.1NS
HbA1c at follow-up (%)7.47 ± 2.598.99 ± 1.947.47 ± 2.19NS
Prevalence on insulin (%)50        39160.02
Total cholesterol at biopsy (mmol/l)5.9 ± 1.35.3 ± 1.65.7 ± 2.1NS
Retinopathy at biopsy (%)70.8*38.59.70.000
Hematuria at biopsy (%)35.323.135.5NS
  • legend

    legend Data are means ± SD, unless otherwise indicated.

  • *

    * Significant difference between groups I and III;

  • significant difference between groups II and III;

  • significant difference between groups I and II. NS, not significant.