Table 5—

Partial Spearman rank correlations between changes in insulin antibodies and HbA1c after 6 months treatment, conditioned on change in total daily insulin dose, or self-monitored morning fasting blood glucose levels at 6 months (in studies 1–3) and at 3 months (in study 4)legend

Study 1Study 2Study 3Study 4
Change in antibodies and HbA1C
    IAsp-specific0.0170.0110.1440.191
    HI-specific−0.016−0.0140.076−0.091
    Cross-reacting−0.074−0.115*−0.1480.142
Change in antibodies and fasting blood glucose
IAsp-specific0.074−0.0260.0970.097
    HI-specific0.0240.0410.079−0.087
    Cross-reacting0.035−0.053−0.222−0.220
  • legend

    legend In the partial correlations the following variables have been conditioned on meal and basal insulin dose (in study 1–3) or breakfast and dinner insulin dose (in study 4) at baseline and after 6 months, baseline self- monitored fasting glucose, and baseline insulin antibodies.

  • *

    * P < 0.01;

  • P < 0.05.