Table 3—

Results

Measurements (n = 17)
Baseline plant protein6 weeks’ plant proteinBaseline animal protein6 weeks’ animal proteinBetween-diet P value*
RPF (ml · min−1 · 1.73 m−2)276 ± 25298 ± 30361 ± 43312 ± 280.21
GFR (ml · min−1 · 1.73 m−2)100 ± 7108 ± 8116 ± 9118 ± 60.63
AER (μg/min)68 ± 3949 ± 2653 ± 2962 ± 280.11
Total cholesterol (mmol/l)4.75 ± 0.194.34 ± 0.184.75 ± 0.234.34 ± 0.220.88
Triglyceride 12.5-h AUC (mg% · h)3,147 ± 4942,839 ± 4633,091 ± 5312,727 ± 4400.99
HDL cholesterol (mmol/l)0.89 ± 0.070.93 ± 0.070.96 ± 0.090.90 ± 0.070.09
HbA1c (%)8.1 ± 0.47.5 ± 0.37.9 ± 0.47.4 ± 0.30.75
Glucose 10.5-h AUC (mg% · h)2,442 ± 2292,075 ± 1352,179 ± 1562,061 ± 1660.12
Insulin 10.5-h AUC (ng/ml)15.0 ± 2.817.0 ± 3.519.1 ± 3.319.0 ± 3.80.44
Systolic blood pressure (mmHg)145 ± 4141 ± 3145 ± 3140 ± 40.90
Diastolic blood pressure (mmHg)83 ± 280 ± 2§82 ± 278 ± 2§0.75
Valine (mmol/l)234.7 ± 11.4224.1 ± 7.8243.3 ± 9.2242.6 ± 11.20.55
Lysine (mmol/l)178.1 ± 15.2160.6 ± 8.6181.4 ± 8.8175.5 ± 12.40.55
  • Data are means ± SE.

  • *

    * Significance of interaction term between diet and time (baseline versus 6 weeks) from three-way repeated-measures ANOVA.

  • Subject 01 had a significantly elevated RPF during the baseline for animal protein versus plant protein. Differences between baselines are not significant with data from subject 01 excluded. Furthermore, differences in RPF between diets at 6 weeks with subject 01 excluded increased P values from 0.21 to 0.72.

  • P < 0.01 vs. baseline;

  • §

    § P < 0.02 vs. baseline.