Table 1—

Clinical and biochemical data in young patients with type 1 diabetes with or without positive thyroid antibodies (anti-TPO ≥100 units/ml or ≥1:100; anti-TG ≥100 units/ml or ≥1:100)

Patients with at least one positive thyroid antibody
Patients without positive thyroid antibodies
NMean ± SD or median (range)NMean ± SD or median (range)
Age (years)1,53013.6 ± 3.8*5,56712.3 ± 4.3
Age at diagnosis (years)1,5308.4 ± 4.0*5,5677.8 ± 4.0
Duration of diabetes (years)1,5305.2 ± 3.9*5,5674.4 ± 3.9
Daily insulin dose (units/kg)1,3450.80 (0.0–2.6)4,7850.80 (0.0–4.3)
Height standard deviation score1,530−0.04 (−3.9 to 3.8)5,567−0.02 (−3.9 to 5.0)
BMI (kg/m2)1,53019.9 (10.0–37.9)5,56718.9 (10.0–45.4)
HbAlc (%)1,5118.1 (3.5–18.5)5,4928.2 (3.5–20.3)
TSH (μU/ml)1,3713.34 (0.0–615.0)*5,1151.84 (0.0–149.0)
TSH >3.5 μU/ml (%)1,53015.8*5,5677.8
Celiac disease (%)1,5300.855,5670.63
  • Data correspond to the most recent data set with positive thyroid antibodies in the DPV-Wiss database.

  • *

    * P < 0.001 compared with patients without positive thyroid antibodies.