Table 2—

Comparison of anthropometry, OGTT, and ITT between PCOS and control subjects

Control
PCOS (BMI <27)
PCOS (BMI ≥27)
Between-group differences
MedianLower quartileUpper quartileMedianLower quartileUpper quartileMedianLower quartileUpper quartilePSignificant between-group differences (P < 0.05)
Age (years)26.523.031.023.519.028.026.523.031.00.03CL
BMI (kg/m2)21.420.523.721.820.324.231.028.733.80.0001CO, LO
WHR77.7975.2783.1887.0082.0093.10100.0095.60103.100.0001CL, CO, LO
G0 (mmol/l)4.404.304.754.704.604.704.704.704.700.004CL, CO
G30 (mmol/l)7.206.757.756.555.507.408.006.808.900.0001CO, LO
G60 (mmol/l)6.355.157.355.454.606.907.206.008.600.02LO
G120 (mmol/l)4.854.155.404.804.005.405.054.105.90NS
G180 (mmol/l)3.653.454.304.103.804.904.103.904.600.01CL, CO
I0 (mIU/l)6.785.6410.508.805.7012.5016.806.0025.700.005*CO, LO
I30 (mIU/l)49.7532.1964.8652.6535.0074.50133.5057.60162.100.00CO, LO
I60 (mIU/l)52.6545.2279.1443.6526.0094.60117.5064.50192.200.0006*CO, LO
I120 (mIU/l)27.0616.9840.7520.3511.7051.8048.3030.20112.200.02*CO, LO
I180 (mIU/l)7.613.7213.089.402.9018.3020.005.9029.200.01CO, LO
Cp0 (nmol/l)0.540.420.720.670.490.881.230.731.510.0001CO, LO
Cp30 (nmol/l)2.451.922.782.691.763.223.532.384.430.0003CO, LO
Cp60 (nmol/l)2.952.503.512.812.263.534.523.174.660.0001CO, LO
Cp120 (nmol/l)2.452.092.622.031.242.763.362.164.040.003CO, LO
Cp180 (nmol/l)0.890.751.471.050.661.441.581.172.370.003CO, LO
AUC-G975.8904.51,051.5919.58161,0241,0569481,1760.005CO, LO
AUC-I/10006.1785.1267.2565.9843.6608.83711.5667.68521.0020.0007*CO, LO
AUCCp394.4351.7436.73349.1303439.8572.4452.3649.80.0001*CO, LO
ΔI/ΔG30–015.4110.0418.32622.9912.9244.8234.80715.5556.6960.0007CL, CO
HOMA-R1.3711.0942.1641.951.3122.6673.46581.2925.79160.007CO, LO
HOMA-F149.2115.6194.67185126.7266.7202.2267.71330.42NS*
Matsuda125.9107.5147.1310684164.655.41832.011180.004CO, LO
FGIR11.607.6613.259.126.2513.125.663.4715.72NS*
FIRI1.230.981.951.751.182.403.091.205.140.05CO, LO
AUC-G/AUC-I0.150.140.180.170.120.250.090.050.130.002*CO, LO
Cederholm63.0054.3277.3771.4755.1586.5251.7540.6462.760.003CO, LO
Suma I98.2873.40116.3073.0050.90133.5161.20121.2307.900.0007*CO, LO
KITT × 1004.814.375.364.933.494.984.533.415.02NS
ITTmin2.001.702.402.402.103.802.502.202.800.004CL, CO
AUCITT64.1859.7072.2074.1370.9086.0074.1971.1075.200.003CL, CO
  • *

    * Due to nonconstant variance even after transformation to minimum skewness of normalized residues with absolute values <2, Kruskal-Wallis test followed by Mann-Whitney U test was used instead of ANOVA. CL, control vs. lean PCOS subjects; CO, control vs. obese PCOS subjects; LO, lean vs. obese PCOS subjects.