Adjusted hazard rate ratios (and 95% CIs) from multivariate Cox models for a given difference in risk factor level for all-cause and cardiovascular mortality
| All-cause mortality | Model 1a (n = 827) | Model 2a (n = 799) | Model 3a (n = 795) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | HR | 95% CI | ||||
| Age (1-year increase) | 1.08 | (1.06–1.10) | 1.08 | (1.05–1.10) | 1.08 | (1.05–1.10) | |||
| Sex (M vs. F) | 1.43 | (1.07–1.90) | 1.45 | (1.07–1.97) | 1.44 | (1.06–1.96) | |||
| Ethnicity and birthplace | |||||||||
| U.S.-born MAs vs. NHWs | 1.66 | (1.15–2.40) | 1.52 | (1.02–2.27) | 1.35 | (0.90–2.03) | |||
| Mexico-born MAs vs. NHWs | 1.14 | (0.63–2.06) | 1.08 | (0.58–2.01) | 0.97 | (0.52–1.81) | |||
| Diabetic medication | |||||||||
| Insulin vs. none | — | — | 2.63 | (1.76–3.94) | 1.69 | (1.05–2.73) | |||
| Oral antidiabetic agents alone versus none | — | — | 1.26 | (0.88–1.81) | 1.04 | (0.71–1.52) | |||
| Current smoker versus others | — | — | 1.53 | (1.11–2.11) | 1.43 | (1.04–1.98) | |||
| Total cholesterol (high vs. low)* | — | — | 1.45 | (1.05–2.00) | 1.36 | (0.98–1.88) | |||
| HDL cholesterol (low vs. high)† | — | — | 1.39 | (1.02–1.89) | 1.22 | (0.89–1.68) | |||
| Systolic blood pressure (an increase of 10 mmHg) | — | — | 1.05 | (0.96–1.16) | 1.09 | (0.99–1.19) | |||
| Duration of diabetes (an increase of 1 year) | — | — | — | — | 1.03 | (1.01–1.05) | |||
| Fasting glucose (an increase of 10 mg/dl) | — | — | — | — | 1.05 | (1.03–1.08) | |||
| Cardiovascular mortality | Model 1b (n = 825) | Model 2b (n = 797) | Model 3b (n = 793) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | HR | 95% CI | ||||
| Age (1-year increase) | 1.07 | (1.04–1.09) | 1.06 | (1.03–1.09) | 1.06 | (1.03–1.09) | |||
| Sex (M vs. F) | 1.45 | (1.01–2.10) | 1.64 | (1.11–2.42) | 1.67 | (1.12–2.47) | |||
| Ethnicity and birthplace | |||||||||
| U.S.-born MAs vs. NHWs | 1.66 | (1.04–2.65) | 1.47 | (0.87–2.47) | 1.29 | (0.76–2.17) | |||
| Mexico-born MAs vs. NHWs | 0.89 | (0.40–2.01) | 0.90 | (0.39–2.09) | 0.83 | (0.36–1.91) | |||
| Diabetic medication | |||||||||
| Insulin vs. none | — | — | 3.31 | (2.02–5.40) | 1.83 | (1.01–3.32) | |||
| Oral antidiabetic agents alone versus none | — | — | 1.27 | (0.78–2.04) | 0.97 | (0.58–1.60) | |||
| History of CVD at index visit (yes versus no) | — | — | 1.65 | (1.07–2.54) | 1.93 | (1.25–2.99) | |||
| Current smoker versus others | — | — | 1.44 | (0.95–2.17) | 1.30 | (0.86–1.98) | |||
| Total cholesterol (high vs. low)* | — | — | 1.81 | (1.21–2.71) | 1.72 | (1.15–2.58) | |||
| HDL cholesterol (low vs. high)† | — | — | 1.61 | (1.09–2.40) | 1.40 | (0.94–2.10) | |||
| Systolic blood pressure (an increase of 10 mmHg) | — | — | 1.13 | (1.00–1.27) | 1.17 | (1.04–1.31) | |||
| Duration of diabetes (an increase of 1 year) | — | — | — | — | 1.04 | (1.01–1.06) | |||
| Fasting glucose (an increase of 10 mg/dl) | — | — | — | — | 1.06 | (1.03–1.09) | |||