Table 1—

Baseline characteristics

Vitamin C treatment groupControl groupP value
n (men/women)19 (17/2)20 (17/3)
Age (years)63.3 ± 2.767.4 ± 2.10.444
Duration of diabetes (years)11.4 ± 1.111.5 ± 1.80.870
BMI (kg/m2)27.6 ± 0.6126.5 ± 0.530.214
Baseline flow 1 (ml · 100 ml−1 · min−1)4.28 ± 0.364.29 ± 0.320.857
Maximum hyperemia flow (ml · 100 ml−1 · min−1)6.8 ± 0.446.04 ± 0.420.270
RH% (%)51.8 ± 4.743.8 ± 4.70.158
Baseline flow 2 (ml · 100 ml−1 · min−1)3.94 ± 0.234.08 ± 0.310.938
Maximum flow after nitrate (ml · 100 ml−1 · min−1)6.56 ± 0.336.42 ± 0.440.406
NTG% (%)66.3 ± 6.7560.8 ± 6.90.563
Vitamin C (μmol/l)39.9 ± 2.039.5 ± 2.10.667
AT III (%)82.3 ± 3.284.6 ± 3.30.422
protein C (%)103.7 ± 5.187.9 ± 8.80.695
protein S (%)96.2 ± 4.689.8 ± 6.00.268
fV (%)144.6 ± 5.7127.7 ± 10.30.822
fVII (%)100.3 ± 8.871.9 ± 9.00.202
Von Willebrand factor (%)133.5 ± 14.5141.0 ± 270.888
PAI-1 (IU/l)3.06 ± 0.362.18 ± 0.400.202
tPA (ng/ml)12.3 ± 0.9912.2 ± 1.30.621
Total cholesterol (mg/dl)217 ± 12215 ± 90.749
HDL (mg/dl)37.3 ± 2.036.1 ± 2.20.496
Fasting glucose (mg/dl)131 ± 17158 ± 140.379
Triglycerides (mg/dl)145 ± 10141 ± 130.550
  • Data are means ± SE. There were no significant differences between the two groups.