Table 1—

Initial subject characteristics

Control groupAe+RTAe only
n9109
Age (years)60.0 ± 2.963.4 ± 2.259.4 ± 1.9
Duration of diabetes (years)4.7 ± 1.23.7 ± 0.93.2 ± 0.6
Number of participants treated with:
 Diet only266
 Single oral agent312
 Two or more oral agents431
Weight (kg)95.6 ± 6.589.5 ± 3.981.2 ± 3.8
BMI (kg/m2)36.7 ± 2.033.3 ± 1.532.5 ± 1.4
Waist circumference (cm)119.0 ± 2.1111.1 ± 2.1106.1 ± 2.3
(Vo2 l/min)1.75 ± 0.121.64 ± 0.101.68 ± 0.11
Glycosylated hemoglobin (%)6.9 ± 0.46.9 ± 0.46.3 ± 0.2
Glucose infusion rate (mg · kg−1 · min−1)2.29 ± 0.462.36 ± 0.332.78 ± 0.49
CT
Total abdominal AT (L4–L5) (cm2)808.4 ± 68.0720.0 ± 42.0616.8 ± 41.9
 Subcutaneous (cm2)549.3 ± 50.8468.9 ± 26.9401.2 ± 42.9
 Visceral (cm2)259.1 ± 34.4251.1 ± 22.9215.7 ± 25.8
Midthigh skeletal muscle
 Cross-sectional area (cm2)225.8 ± 8.9208 ± 10.0224.1 ± 15.8
 Low-density muscle (cm2)50.6 ± 4.251.3 ± 6.749.4 ± 7.3
 Normal-density muscle (cm2)175.3 ± 7.5156.6 ± 12.8174.8 ± 11.1
  • Data are n or means ± SE.