Table 1—

Demographic, clinical, biochemical, and autoimmune characteristics by race

VariableBlack subjectsWhite subjectsP
n113117
Age at onset (years)10 ± 4.110 ± 4.00.97
Male/female (%)53/4751/490.78
Obesity (BMI ≥85th percentile; %)*43110.00005
Tanner stage 4 or 5 (%)38280.13
Acanthosis nigricans (%)2110.0003
Insulin dosage at discharge (units/kg)0.91 ± 0.460.88 ± 0.390.61
Parent with diabetes (%)§29210.24
Family history of diabetes (%)§81750.35
Ketones (%)71790.2
Bicarbonate level (meq/l)17.1 ± 7.917.4 ± 7.20.78
Acidosis (% bicarbonate <18 meq/l)35430.35
Cholesterol level (mg/dl)184 ± 39179 ± 430.42
≥1 conventional β-cell AA (%)70890.0002
ICA(H)+ (%)58770.001
GAD65 AA+ (%)54730.004
IA-2 AA+ (%)38650.0001
IAA+ (%)20350.21
GAD AA + IA-2 AA (%)29510.001
ICA(H)+ GAD65 AA+ IA-2 AA (%)29470.007
  • Data are means ± SD unless otherwise noted. Data available for indicated number of black and white subjects, respectively:

  • * 96 and 89;

  • 105 and 103;

  • 67 and 69;

  • § 89 and 84;

  • 52 and 59;

  • 109 and 106.