Table 1—

Baseline demographic and clinical characteristics of each study group

CharacteristicsMetformin
Placebo
Run inRandomizationRun inRandomization
n14
13
Age (years)15.7 ± 1.915.9 ± 1.915.9 ± 1.716 ± 1.7
Sex (F/M)8/6
6/7
Duration of diabetes (years)9.7 ± 4.49.9 ± 4.46.9 ± 3.87 ± 3.8
Weight (kg)62.9 ± 13.763.3 ± 13.671.2 ± 11.771.6 ± 11.7
BMI (kg/m2)22.7 ± 4.122.8 ± 4.225.4 ± 2.925.7 ± 2.9
Pubertal status (Tanner2–3/Tanner4–5)5/9
5/8
HbA1c (%)9.4 ± 19.3 ± 1.48.9 ± 0.88.6 ± 0.8
Insulin dosage (units · kg−1 · day−1)1.2 ± 0.21.21 ± 0.31.3 ± 0.21.28 ± 0.19
SI (× 10−4 · min−1 · μU−1 · ml−1)1.7 (CI 1.0–2.6)
1.1 (CI 0.6–2.2)
  • Data are means ± SD, except SI, which is expressed as geometric mean and 95% CI.