Table 4—

Anthropometric and metabolic characteristics of high-risk subjects from the follow-up phase of the Sandy Lake Health and Diabetes Project (men = 29, women = 66) and associations between baseline levels of adiponectin with follow-up levels and changes over time in these variables

VariableBaseline valuesChange over 4-year follow-up periodCorrelation between baseline adiponectin and level of metabolic variable at follow-up
Correlation between baseline adiponectin and change in metabolic variable at follow-up
Partial rP valuePartial rP value
NGT/IGT/diabetes (n)41/54/054/17/24
Age at baseline (years)35.1 ± 17.0
Adiponectin (μg/ml)11.7 (8.8–16.2)
Body fat (%)41.5 ± 10.66.0 (0.1–10.1)−0.010.920.040.73
Waist (cm)96.4 ± 11.43.4 (−0.5 to 6.5)0.150.160.140.19
HOMA-IR (units)4.8 (3.4–6.7)−0.3 (−1.9 to 0.6)−0.41<0.0001−0.290.009
Triglyceride (mmol/l)1.5 (1.1–1.9)0.1 (−0.3 to 0.4)−0.030.79−0.070.52
HDL cholesterol (mmol/l)1.2 ± 0.30.0 (−0.1 to 0.2)0.210.05580.240.0341
  • Data are means ± SD or median (interquartile range). Spearman correlation analysis, sample sizes vary slightly due to occasional missing values. High risk defined as subjects with baseline IGT or NGT with a 2-h postchallenge glucose concentration of ≥7.0 mmol/l.

  • Analyses adjusted for age, sex, change in waist circumference, baseline and follow-up diabetes status, and baseline level of the dependent follow-up variable;

  • analyses adjusted for age, sex, change in waist circumference, baseline and follow-up diabetes status, and baseline level of the dependent change variable.