Table 1—

Subject characteristics of pre- and postmenopausal women with and without diabetes

Women without diabetes
Women with diabetes
Significant difference + diabetes
PremenopausalPostmenopausalPremenopausalPostmenopausalPremenopausalPostmenopausal
n8888
Age (years)42 (34–56)*58 (46–68)39 (32–54)*61 (53–70)NSNS
Weight (kg)64.6 (52.7–121.9)77.7 (56.8–96.7)102.8 (59.8–123.1)82.8 (76.9–105.8)0.01NS
BMI (kg/m2)26.5 (21.7–42.2)30 (21.9–37.3)37.8 (23.1–46.3)32.6 (27.9–35.2)0.01NS
HbA1c (%)NDND9.1 (6.8–14.8)8 (6.0–9.1)
Fasting values
 Glucose (mmol/l)5.4 (5.2–6.1)5.3 (4.6–6.1)9.9 (5.6–14.0)10.5 (7.5–17.9)0.010.05
 Insulin10.7 (4.8–12.3)7.9 (5–34.3)12.8 (4.5–28.5)13.6 (9.1–31.3)NSNS
 Triglycerides (mmol/l)0.9 (0.7–2.2)1.6 (0.5–2.7)2.2 (1.7–3.0)2.4 (1.6–5.8)0.010.05
 NEFA (mmol/l)163 (75.3–198.5)113.9 (84.2–141.9)189.5 (169.4–244.1)194 (129.1–327.4)0.010.01
 Total cholesterol (mmol/l)4.7 (3.8–6.9)*6.6 (4.8–9.3)4.8 (3.6–6.6)5.1 (4.0–6.8)NS0.01
 HDL cholesterol (mmol/l)1.8 (1.1–2.3)1.5 (1.1–2.2)1.0 (0.7–1.5)1.1 (0.8–1.3)0.010.01
  • Values shown are median (range). Superscript denotes significantly different from postmenopausal women within corresponding group by Kruskal-Wallis ANOVA:

  • * P < 0.01;

  • P < 0.05. ND, HbA1c not determined in women without diabetes; NS, not significant. The significance of differences between women with and without diabetes for the corresponding menopausal status is also shown.