Table 2—

Results of 28 treatments with conventional wound care or maggot therapy

Conventional therapyMDT
n wounds monitored1414
Average duration of therapy (weeks)5.3 (4.1–6.4)4.7 (3.5–6.0)
Debridement
 Initial necrotic tissue (% total area)44 (22–67)38 (22–55)
 Initial surface area of necrotic tissue (cm2)2.7 (1.2–4.4)5.0 (2.0–8.0)
 Necrotic tissue (% total surface area) at week 239 (19–58)*7 (1–13)*
 Percent change in surface area of necrotic tissue+8% (−8 to 25)*−59 (−125 to 7)*
 Weekly change in surface area of necrotic tissue (cm2)+0.4 (−0.4 to 1.2)−3.9 (−8.4 to −0.6)
Wound size and healing
 Initial surface area (cm2)6.3 (4.2–8.5)13.3 (6.4–20.2)
 Surface area at 4 weeks (cm2)10.9 (6.1–15.7)11.8 (4.8–18.7)
 Change in surface area (cm2)+5.0 (0.19–9.8)*−3.8 (−7.0 to 0.6)*
 Weekly change in surface area (cm2)+1.15 (0.24–2.1)*−0.78 (−1.6 to 0.1)*
 Weekly % change in surface area (final/initial)+27 (4.1–50)−2 (−22 to 18)
 Healing rate at 4 weeks−0.08 (−0.15 to −0.0002)*0.08 (0.20–0.14)*
 Healing rate at 8 weeks−0.02 (−0.08 to 0.04)*0.07 (0.04–0.11)*
 Wounds completely closed (%)21 (0–44)36 (7–65)
 Average time until wound closure (weeks)18 (8–28)15 (3–26)
Quality of wound base: preparation for graft or surgical closure
 Initial granulation tissue (% total area)18 (2–33)19 (4–35)
 Granulation tissue at 4 weeks (% total area)15 (1–30)*56 (34–77)*
  • Data are means (median and range), unless otherwise specified. Six wounds received conventional therapy only, six received maggot therapy only, and eight received conventional therapy followed by maggot therapy.

  • *

    * Differences in mean values where the probability (P) of a type I error is ≤ 0.05.