Table 2—

Comorbid conditions in diabetic veterans with and without amputations

CharacteristicsDiabetesIncident amputationPrevalent amputation
Comorbid conditions
 Hypertension286,862 (67.2)2,472 (75.2)*6,942 (72.9)
 Cardiovascular disease172,968 (40.5)1,966 (59.8)*5,056 (53.1)
 Stroke31,227 (7.3)570 (17.3)*1,360 (4.3)
 Cancer49,214 (11.5)350 (10.6)1,059 (11.1)
 COPD64,542 (15.1)659 (20.0)*1,624 (17.0)
 Depression50,971 (11.9)417 (12.7)1,035 (10.9)
Renal disease
 ESRD17,117 (4.0)519 (15.8)*1,498 (52.9)
 Diabetic nephropathy7421 (1.7)206 (6.3)575 (20.3)
 HTN renal disease1,286 (0.3)48 (1.5)73 (2.6)
 Interstitial nephritis4,656 (1.1)21 (0.6)65 (2.3)
 Acute renal failure1,849 (0.4)92 (2.8)129 (4.6)
 Renal cell carcinoma1,264 (0.3)12 (0.4)19 (0.7)
 Other9,078 (1.1)165 (5.1)473 (16.7)
Background retinopathy40,194 (9.4)659 (20.0)*2,198 (23.1)
Blindness11,403 (2.7)164 (5.0)*600 (6.3)
Hospitalizations1.58 ± 1.092.38 ± 1.55*1.93 ± 1.41
Number of visits18.9 ± 20.231.0 ± 25.4*26.95 ± 26.79
Mortality25,292 (5.9)718 (21.8)*1,761 (18.5)
  • Data are n (%) or means ± SD.

  • *

    * P < 0.005, significant for trend within categories as determined by χ2 tests or for the mean of continuous variables using independent t test for veterans with incident amputations versus veterans without amputations.

  • P < 0.005 significant for trend within categories as determined by χ2 tests or for the mean of continuous variables using independent t test for veterans with previous amputations versus veterans without amputations. HTN, hypertensive.