Table 1—

Baseline characteristics of study subjects by type 2 diabetes status at follow-up at 5–6 and 10 years

Baseline variableDiabetes status at 5- to 6-year follow-up
Diabetes status at 10-year follow-up
Diabetic (n = 50)Nondiabetic (n = 415)P valueDiabetic (n = 74)Nondiabetic (n = 338)P value
Age (years)58.9 ± 1.5 (62.6)51.3 ± 0.6 (52.5)<0.00157.5 ± 1.3 (60.9)50.6 ± 0.6 (49.0)<0.001
Female sex26 (52.0)196 (47.2)0.52330 (40.5)167 (49.4)0.167
Family history*30 (60.0)175 (42.2)0.01646 (62.2)135 (39.9)<0.001
BMI (kg/m2)24.9 ± 0.5 (25.1)24.0 ± 0.2 (23.7)0.10025.1 ± 0.4 (25.0)23.9 ± 0.2 (23.6)0.007
Systolic blood pressure (mmHg)139 ± 2 (138.5)128 ± 1 (125)<0.001137 ± 3 (134)127 ± 1 (124)<0.001
Diastolic blood pressure (mmHg)80 ± 1 (80)76 ± 1 (76)0.02180 ± 1 (80.5)76 ± 1 (76)<0.001
FPG (mmol/l)5.5 ± 0.1 (5.6)5.1 ± 0.0 (5.1)<0.0015.6 ± 0.1 (5.6)5.1 ± 0.0 (5.0)<0.001
IFG7 (14.0)23 (5.5)0.02118 (24.3)10 (3.0)<0.001
2-h glucose (mmol/l)9.0 ± 0.2 (8.6)7.1 ± 0.1 (7.0)<0.0018.8 ± 0.2 (8.7)6.9 ± 0.1 (6.9)<0.001
IGT45 (90.0)133 (32.1)<0.00159 (79.7)98 (29.0)<0.001
Cholesterol (mmol/l)6.10 ± 0.15 (6.15)5.80 ± 0.05 (5.70)0.0376.10 ± 0.15 (5.90)5.75 ± 0.05 (5.65)0.021
HDL cholesterol (mmol/l)1.45 ± 0.05 (1.35)1.50 ± 0.00 (1.45)0.5991.40 ± 0.05 (1.30)1.55 ± 0.00 (1.45)0.007
LDL cholesterol (mmol/l)3.80 ± 0.15 (3.75)3.60 ± 0.05 (3.55)0.2113.85 ± 0.10 (3.85)3.60 ± 0.05 (3.55)0.049
Triglycerides (mmol/l)2.02 ± 0.34 (1.40)1.52 ± 0.06 (1.24)0.3331.96 ± 0.18 (1.44)1.46 ± 0.06 (1.18)0.002
  • Data are means ± SE (medians) or n (column %).

  • *

    * Parent or sibling with type 2 diabetes.