Table 1—

Clinical and metabolic parameters measured at the end of each 4-week alcohol period

Baseline alcohol intakeLow alcohol intakeUsual alcohol intake
Alcohol intake (g/day)68.1 ± 4.67.9 ± 1.6*72.4 ± 5.0
Weight (kg)84.1 ± 1.683.0 ± 1.583.9 ± 1.6
HDLC (mmol/l)1.35 ± 0.081.13 ± 0.07*1.36 ± 0.07
γ-GT (units/l)24.4 (20.0–29.8)18.6 (15.5–22.2)*24.4 (19.7–30.2)
Fasting glucose (mmol/l)5.1 ± 0.15.0 ± 0.15.0 ± 0.1
Fasting insulin (pmol/l)36 ± 434 ± 633 ± 3
ISI (ml/kg · min−1 · pmol/l) × 10317.7 (13.3–23.7)18.8 (13.1–26.9)20.2 (13.8–29.5)
HOMA score1.05 (0.83–1.33)0.93 (0.69–1.24)0.86 (0.58–1.27)
Gss (mmol/l)5.2 ± 0.15.1 ± 0.15.0 ± 0.1
Iss (pmol/l)242 ± 15244 ± 23230 ± 22
Fructosamine (μmol/l)219 ± 4227 ± 5223 ± 5
  • Data are means ± SE and geometric mean (95% CI). Significant differences

  • *

    * P < 0.001,

  • P < 0.05 from usual alcohol intake (paired t test low alcohol intake versus usual alcohol intake). n = 16 except for ISI, Gss, and Iss, where n = 12.