Table 2—

Baseline characteristics as risk for mortality and the diabetes-related end point

VariableMortality
Diabetes-related end point
PRR (95% CI)PRR (95% CI)
Male sex0.0142.400 (1.187–4.849)0.0701.759 (0.954–3.241)
Age0.0071.090 (1.024–1.160)0.0011.098 (1.039–1.160)
Current BMI0.2750.941 (0.845–1.049)0.0270.894 (0.809–0.988)
Past maximum BMI0.5511.030 (0.934–1.136)0.7261.016 (0.931–1.107)
ΔBMI0.0331.139 (1.011–1.284)0.0091.155 (1.037–1.287)
Duration of diabetes0.5661.010 (0.976–1.045)0.8151.004 (0.973–1.035)
Family history of diabetes0.2380.659 (0.330–1.317)0.9410.977 (0.533–1.791)
Plasma glucose0.1521.004 (0.999–1.009)0.0211.006 (1.001–1.010)
HbA1c0.5710.911 (0.661–1.256)0.9270.987 (0.748–1.303)
Creatinine<0.00013.232 (2.240–4.664)<0.00013.346 (2.395–4.674)
Total cholesterol0.4270.996 (0.987–1.006)0.2991.005 (0.996–1.013)
HDL cholesterol0.2800.987 (0.965–1.010)0.1930.986 (0.966–1.007)
LDL cholesterol0.2050.993 (0.983–1.004)0.2361.006 (0.996–1.015)
Triglycerides0.1531.002 (0.999–1.006)0.1901.002 (0.999–1.005)
Blood pressure
 SBP0.4610.992 (0.972–1.013)0.4761.007 (0.988–1.026)
 Diastolic blood pressure0.8100.996 (0.961–1.032)0.1400.976 (0.945–1.008)
 Mean pressure0.5840.991 (0.959–1.024)0.5780.992 (0.963–1.021)
Hypoglycemic agents0.9611.024 (0.396–2.645)0.8010.901 (0.400–2.029)
 Oral hypoglycemics0.9441.024 (0.521–2.016)0.4790.804 (0.439–1.472)
 Sulfonylurea0.9540.980 (0.500–1.923)0.7480.905 (0.493–1.662)
 α-Glucosidase inhibitor0.4271.430 (0.529–3.454)0.5010.702 (0.250–1.966)
 Metformin0.3770.408 (0.056–2.987)0.5860.674 (0.163–2.788)
 Insulin0.9450.976 (0.489–1.950)0.6960.882 (0.447–1.658)
Microangiopathy0.8621.073 (0.486–2.370)0.0492.560 (1.006–6.514)
 Retinopathy
  Background0.2021.576 (0.784–3.170)0.0122.188 (1.186–4.037)
  Proliferative0.8541.118 (0.340–3.670)0.7611.174 (0.418–3.293)
 Neuropathy0.7690.898 (0.438–1.842)0.0242.711 (1.142–6.436)
 Macroproteinuria0.0023.659 (1.848–7.243)0.00033.113 (1.685–5.753)
Microalbuminuria0.0242.346 (1.117–4.930)0.0272.883 (1.444–5.754)
Macroangiopathy0.0032.752 (1.405–5.390)0.0012.753 (1.503–5.041)
 Myocardial infarction0.8871.071 (0.415–2.768)0.9761.013 (0.427–2.405)
 Stroke<0.00014.105 (2.072–8.129)<0.00014.085 (2.205–7.570)
Antihypertensive agents0.7671.109 (0.560–2.195)0.4071.302 (0.698–2.427)
 Ca2+ channel blocker0.3561.374 (0.700–2.694)0.3011.376 (0.751–2.522)
 ACEI0.2811.472 (0.729–2.975)0.3341.372 (0.722–2.605)
Smoking
 No0.0020.324 (0.160–0.695)0.0420.534 (0.291–0.979)
 Ex0.2291.626 (0.736–3.591)0.3321.440 (0.689–3.010)
 Current0.0072.579 (1.302–5.106)0.1211.677 (0.872–3.227)
Malignancy0.3591.630 (0.574–4.628)0.4770.597 (0.144–2.472)
  • ACEI, ACE inhibitor.