Table 1—

Characteristics of study subjects at baseline according to whether IGT developed after a 10- to 11-year follow-up

Total (n = 128)IGT status after follow-up
Crude OR (95% CI)P
Not IGT (n = 71)IGT (n = 57)
Age (years)39.5 ± 4.139.9 ± 4.139.1 ± 4.10.83 (0.58–1.19)0.312
Female sex (%)46.947.945.60.91 (0.45–1.84)0.798
Family history of diabetes29.728.231.61.18 (0.55–2.52)0.675
Metabolic variables
 HOMA-IR2.78 ± 1.542.40 ± 1.053.24 ± 1.891.94 (1.23–3.06)0.005
 IIR57.4 ± 44.759.9 ± 48.654.4 ± 39.40.88 (0.61–1.26)0.489
 FPG (mmol/l)4.83 ± 0.494.76 ± 0.474.91 ± 0.501.38 (0.96–1.99)0.082
Adipose variables
 Thoracic subcutaneous fat (cm2)75.3 ± 52.067.0 ± 43.485.9 ± 59.91.50 (1.00–2.25)0.052
 Abdomen subcutaneous fat (cm2)139.3 ± 70.2125.0 ± 63.5157.0 ± 74.61.63 (1.11–2.39)0.013
 Intra-abdominal fat (cm2)50.8 ± 32.145.0 ± 29.658.1 ± 33.81.52 (1.06–2.19)0.024
 Left thigh subcutaneous fat (cm2)66.4 ± 33.266.5 ± 31.666.3 ± 35.40.99 (0.70–1.41)0.975
 Total subcutaneous fat (cm2)346.1 ± 164.5325.0 ± 146.7372.9 ± 182.61.35 (0.94–1.95)0.109
 Total fat (cm2)396.9 ± 178.5370.0 ± 162.8431.1 ± 192.71.43 (0.98–2.07)0.060
 BMI (kg/m2)23.4 ± 2.923.2 ± 2.723.7 ± 3.01.22 (0.85–1.73)0.278
 Waist circumference (cm)82.7 ± 8.481.7 ± 1.084.1 ± 1.11.34 (0.93–1.92)0.113
  • Data are means ± SD or % unless otherwise indicated. ORs for continuous variables reflect a 1-SD magnitude increase. Total subcutaneous fat and total fat areas represent sums of adipose tissue areas as determined by multiple CT slices described in the text. HOMA-IR is based on the homeostasis model: HOMA-IR = (fasting glucose [in millimoles per liter]) (fasting insulin [in microunits per liter])/22.5). The P value is for univariate logistic regression analysis.